Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2962266 | 0.87 | SMN1; SMN2 (0.60) | TDP1HTTSMN1; SMN2LMNACYP19A1 | |
| SCHEMBL16956994 | 0.84 | SMN1; SMN2 (0.57) | TDP1HTTSMN1; SMN2LMNACYP19A1 | |
| SCHEMBL6676325 | 0.84 | SMN1; SMN2 (0.57) | TDP1HTTSMN1; SMN2LMNACYP19A1 | |
| SCHEMBL17374954 | 0.82 | TDP1 (0.58) | TDP1HTTSMN1; SMN2LMNACYP19A1 | |
| SCHEMBL13332291 | 0.82 | TDP1 (0.44) | TDP1HTTSMN1; SMN2LMNACYP19A1 | |
| SCHEMBL14079397 | 0.81 | SMN1; SMN2 (0.55) | TDP1HTTSMN1; SMN2LMNACYP19A1 | |
| SCHEMBL1148691 | 0.81 | TDP1 (0.54) | TDP1HTTSMN1; SMN2LMNACYP19A1 | |
| SCHEMBL17165030 | 0.80 | MEN1 (0.55) | TDP1HTTSMN1; SMN2LMNAPTGS2 | |
| SCHEMBL17165032 | 0.80 | MEN1 (0.55) | TDP1HTTSMN1; SMN2LMNAPTGS2 | |
| SCHEMBL7801213 | 0.80 | TDP1 (0.52) | TDP1HTTSMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109156471-B | Application of 1, 3-dimethyl-1H-pyrazole-4-amide derivative in preparation of herbicide | 浙江工业大学 | 2020-12-15 | — | — | CN | disclosed |