Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804239 | 0.88 | TDP1 (0.51) | TDP1GAAMAPTKMT2AALDH1A1 | |
| SCHEMBL7801371 | 0.86 | TDP1 (0.49) | TDP1GAAMAPTMEN1KMT2A | |
| SCHEMBL7803614 | 0.85 | MAPT (0.46) | TDP1GAAMAPTMEN1KMT2A | |
| SCHEMBL7802202 | 0.82 | APP (0.55) | TDP1GAAMAPTMEN1KMT2A | |
| SCHEMBL28517356 | 0.80 | TDP1 (0.61) | TDP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7801278 | 0.78 | NFE2L2 (0.55) | TDP1MAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7787525 | 0.77 | NFE2L2 (0.53) | TDP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2962266 | 0.76 | SMN1; SMN2 (0.60) | TDP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7802203 | 0.76 | SMN1; SMN2 (0.49) | TDP1GAAMAPTKMT2AALDH1A1 | |
| SCHEMBL7805414 | 0.75 | NFE2L2 (0.46) | TDP1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |