Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23717434 | 0.88 | LMNA (0.52) | SMN1; SMN2LMNATDP1HTTCYP1A2 | |
| SCHEMBL1148691 | 0.84 | TDP1 (0.54) | SMN1; SMN2LMNATDP1HTTCYP1A2 | |
| SCHEMBL2962266 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNATDP1HTTCYP1A2 | |
| SCHEMBL16956994 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNATDP1HTTCYP1A2 | |
| SCHEMBL6676325 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNATDP1HTTCYP1A2 | |
| SCHEMBL28517356 | 0.81 | TDP1 (0.61) | SMN1; SMN2LMNATDP1HTTCYP1A2 | |
| SCHEMBL17374954 | 0.80 | TDP1 (0.58) | SMN1; SMN2LMNATDP1HTTCYP1A2 | |
| SCHEMBL8041378 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNATDP1HTTALDH1A1 | |
| SCHEMBL10438569 | 0.80 | TDP1 (0.51) | LMNATDP1HTTCYP3A4ALDH1A1 | |
| SCHEMBL3229107 | 0.79 | THRB (0.52) | SMN1; SMN2LMNATDP1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200222406-A1 | METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS | DALCOR PHARMA UK LTD., STOCKPORT ZUG BRANCH (CH) | 2020-07-16 | — | — | US | disclosed |
| US-7414146-B2 | Imaging element containing a blocked photographically useful compound | CARESTREAM HEALTH, INC. (US) | 2008-08-19 | — | — | US | disclosed |
| US-7189502-B1 | Radiographic materials with antifoggant precursors | EASTMAN KODAK COMPANY (US) | 2007-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200222406-A1 | METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS | HMGCR, PCSK9, FABP3 | SMN1; SMN2 2041/4885LMNA 227/4885TDP1 1557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.