Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28509684 | 1.00 | DPP4 (0.39) | DPP4TAS1R3TAS1R1PDE4APDE4B | |
| SCHEMBL20178572 | 0.86 | MET (0.40) | DPP4TAS1R3TAS1R1METKDM4E | |
| SCHEMBL3550245 | 0.84 | CA12 (0.53) | TAS1R3TAS1R1ADRB2ADRB1ADRB3 | |
| SCHEMBL28511670 | 0.84 | RARB (0.46) | ADRB1ADRB3KMT2AALDH1A1 | |
| SCHEMBL28511668 | 0.84 | RARB (0.46) | ADRB1ADRB3KMT2AALDH1A1 | |
| SCHEMBL31455721 | 0.80 | CA12 (0.42) | DPP4METKDM4EKMT2ACA12 | |
| SCHEMBL1498779 | 0.79 | CA12 (0.43) | DPP4METKDM4EKMT2ACA12 | |
| SCHEMBL7220810 | 0.79 | MAPT (0.47) | DPP4METKDM4ECA12CA1 | |
| SCHEMBL14893204 | 0.77 | CA12 (0.42) | DPP4METKDM4EKMT2ACA12 | |
| SCHEMBL15133703 | 0.76 | PDE4D (0.53) | TAS1R3TAS1R1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107235960-B | Amide derivatives, preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2021-01-29 | — | — | CN | disclosed |