SCHEMBL28518014

SCHEMBL28518014

CCc1cccc(C(O)O)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.39
PARP1 P09874 1/20 0.38
HRH4 Q9H3N8 1/20 0.35
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34
CXCR4 P61073 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
CHRNB2 P17787 2/20 0.33
CHRNB4 P30926 2/20 0.33
CHRNA3 P32297 2/20 0.33
CHRNA4 P43681 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27270503 0.86 PARP1 (0.37) KCNH2PARP1HRH4GRIN2DGRIN3B
SCHEMBL23343749 0.83 ADORA2A (0.37) KCNH2PARP1HRH4CXCR4NOS1
SCHEMBL1581851 0.81 KCNH2 (0.36) KCNH2PARP1HRH4GRIN2DGRIN3B
SCHEMBL31481285 0.81 KCNH2 (0.36) KCNH2PARP1HRH4GRIN2DGRIN3B
SCHEMBL24453820 0.80 GABRA1 (0.39) KCNH2NOS1NOS2NPSR1GABRA1
SCHEMBL15832403 0.80 IRAK4 (0.39) KCNH2PARP1HRH4CXCR4GABRA1
SCHEMBL13178690 0.79 NOS1 (0.37) KCNH2PARP1HRH4GRIN2DGRIN3B
Ammonia Solution, Strong SCHEMBL7989286 0.79 KCNH2 (0.35) KCNH2PARP1HRH4GRIN2DGRIN3B
SCHEMBL20738454 0.79 PARP1 (0.35) KCNH2PARP1HRH4GRIN2DGRIN3B
SCHEMBL22895136 0.78 KCNH2 (0.34) KCNH2PARP1HRH4CXCR4NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112390825-B Metal organic complex with near-infrared absorption and emission performance and preparation method thereof 武汉大学 2021-09-14 CN disclosed
CN-112390825-A Metal organic complex with near-infrared absorption and emission performance and preparation method thereof 武汉大学 2021-02-23 CN disclosed