Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631691 | 0.77 | PTPN2 (0.51) | RAB9APTPN2PTPN1PTPN6NPC1 | |
| SCHEMBL17631872 | 0.77 | PTPN2 (0.50) | KMT2ARAB9AMEN1SMN1; SMN2PTPN2 | |
| SCHEMBL28898382 | 0.75 | NPC1 (0.62) | KMT2ARAB9AMEN1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28535988 | 0.75 | MEN1 (0.57) | KMT2ARAB9AMEN1GAASMN1; SMN2 | |
| SCHEMBL28519087 | 0.74 | MEN1 (0.67) | KMT2ARAB9AMEN1GAASMN1; SMN2 | |
| SCHEMBL28531349 | 0.74 | RAB9A (0.66) | KMT2ARAB9AMEN1GAASMN1; SMN2 | |
| SCHEMBL28497363 | 0.73 | MKNK1 (0.67) | PTPN2PTPN1PTPN6 | |
| SCHEMBL19296045 | 0.73 | MKNK1 (0.67) | PTPN2PTPN1PTPN6 | |
| SCHEMBL6247527 | 0.73 | PTPN2 (0.49) | KMT2ARAB9AMEN1SMN1; SMN2PTPN2 | |
| SCHEMBL28148326 | 0.73 | STAT3 (0.56) | KMT2ARAB9AMEN1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503569-B | Thiazole derivative and preparation method and application thereof | 山东大学 | 2021-01-15 | — | — | CN | disclosed |