Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | GSK3A | P49840 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28519087 | 0.89 | MEN1 (0.67) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28908921 | 0.88 | MEN1 (0.68) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28525534 | 0.87 | RAB9A (0.67) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28531250 | 0.87 | KMT2A (0.67) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28531603 | 0.87 | SMN1; SMN2 (0.67) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28524552 | 0.81 | KMT2A (0.62) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28518118 | 0.74 | KMT2A (0.55) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30597555 | 0.74 | MAPT (0.68) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28573043 | 0.74 | MEN1 (0.75) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12081852 | 0.72 | MAPT (0.74) | RAB9ANPC1SMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503569-B | Thiazole derivative and preparation method and application thereof | 山东大学 | 2021-01-15 | — | — | CN | claimed |
| CN-109503569-B | Thiazole derivative and preparation method and application thereof | 山东大学 | 2021-01-15 | — | — | CN | disclosed |