Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 16/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | ITK | Q08881 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28514105 | 0.87 | GRIN2B (0.44) | GRIN2BGRIN1TGFBR1BTK | |
| SCHEMBL28517085 | 0.84 | GRIN2B (0.43) | GRIN2BGRIN1TGFBR1 | |
| SCHEMBL28523488 | 0.75 | AXL (0.44) | GRIN2B | |
| SCHEMBL29901520 | 0.75 | GRIN2B (0.44) | GRIN2BGRIN1TGFBR1 | |
| SCHEMBL28516948 | 0.73 | BRD4 (0.50) | GRIN2BGRIN1TGFBR1BTK | |
| SCHEMBL15942809 | 0.71 | CCR1 (0.41) | — | |
| SCHEMBL29525440 | 0.70 | TGFBR1 (0.52) | GRIN2BGRIN1TGFBR1 | |
| SCHEMBL22771445 | 0.70 | TGFBR1 (0.52) | GRIN2BGRIN1TGFBR1 | |
| SCHEMBL22198980 | 0.69 | GRIN2B (0.48) | GRIN2BGRIN1BTK | |
| SCHEMBL22775718 | 0.69 | GRIN2B (0.49) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026094-B | Substituted 4-azaindoles and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2021-02-09 | — | — | CN | disclosed |