SCHEMBL28518367

SCHEMBL28518367

O=C=C1C(=C=O)c2ccc3ccccc3c2C(C(=O)O)C1=C=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
HIF1A Q16665 1/20 0.34
WDR5 P61964 1/20 0.34
AKR1B1 P15121 2/20 0.34
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
CSNK2A1 P68400 1/20 0.34
ALDH1A1 P00352 2/20 0.33
NR4A1 P22736 2/20 0.33
DNMT1 P26358 1/20 0.33
LDHA P00338 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
RCE1 Q9Y256 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28516571 0.74 POLB (0.35)
SCHEMBL28507414 0.73 HDAC3 (0.40) CYP1A2ALDH1A1KDM4EMAPTMEN1
SCHEMBL28514367 0.72 POLB (0.33)
SCHEMBL5971471 0.69 CYP1A2 (0.49) CYP1A2CYP2D6CYP2C9CYP2C19HIF1A
SCHEMBL7155154 0.68 CYP19A1 (0.48) CYP1A2CYP2D6CYP2C9CYP2C19HIF1A
SCHEMBL16099176 0.63 CSNK2A2 (0.38) CYP1A2CYP2C19WDR5AKR1B1CSNK2A2
Phenanthrene SCHEMBL28735113 0.61 ALDH1A1 (0.71) CYP1A2CYP2D6CYP2C19HIF1AWDR5
Phenanthrene SCHEMBL30702393 0.61 ALDH1A1 (0.71) CYP1A2CYP2D6CYP2C19HIF1AWDR5
SCHEMBL8817146 0.60 ATM (0.49) CYP1A2CYP2D6CYP2C9CYP2C19HIF1A
SCHEMBL1661024 0.59 HSD17B10 (0.63) CYP1A2CYP2C19WDR5ALDH1A1NR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108008600-B Radiation-sensitive composition 三菱瓦斯化学株式会社 2021-02-09 CN disclosed