Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28305259 | 0.77 | CYP1A2 (0.37) | CYP19A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7154204 | 0.75 | WDR5 (0.45) | CYP19A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30356308 | 0.71 | KIF11 (0.39) | CYP19A1ALDH1A1HSD17B10KDM4ESIRT2 | |
| SCHEMBL7220291 | 0.71 | ACHE (0.40) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL28850201 | 0.69 | ALDH1A1 (0.53) | CYP19A1ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL916737 | 0.69 | ALDH1A1 (0.53) | CYP19A1ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL28518367 | 0.68 | CYP1A2 (0.34) | CYP19A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13938126 | 0.68 | ACHE (0.45) | ALDH1A1MEN1HPGDKMT2AHSD17B10 | |
| SCHEMBL2791039 | 0.68 | CYP1A2 (0.54) | CYP1A2CYP2D6CYP2C9CYP2C19HIF1A | |
| SCHEMBL5971471 | 0.66 | CYP1A2 (0.49) | CYP1A2CYP2D6CYP2C9CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534627-B1 | Using FMOC (9-fluorenylmethyloxycarbonyl) and tert-butyl containing compounds as protecting group; efficiency and storage stability | RESEARCH CORPORATION TECNOLOGIES, INC. | 2003-03-18 | — | — | US | disclosed |