Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1078967 | 1.00 | ALDH1A1 (0.33) | ALDH1A1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL1080369 | 0.91 | CYP1A2 (0.32) | CYP1A2HIF1A | |
| SCHEMBL1077674 | 0.91 | CYP1A2 (0.32) | CYP1A2HIF1A | |
| SCHEMBL1078611 | 0.91 | CYP1A2 (0.32) | CYP1A2HIF1A | |
| SCHEMBL1080848 | 0.80 | INPP5A (0.33) | — | |
| SCHEMBL1080565 | 0.79 | SERPINE1 (0.38) | ALDH1A1CYP1A2HIF1ATSHRSMN1; SMN2 | |
| SCHEMBL9216168 | 0.79 | CHRM2 (0.36) | ALDH1A1CYP1A2HIF1ATSHRCHRM2 | |
| SCHEMBL1079969 | 0.78 | ALDH1A1 (0.33) | ALDH1A1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL1079831 | 0.77 | TSHR (0.40) | ALDH1A1TSHR | |
| SCHEMBL2428874 | 0.76 | INPP5A (0.31) | CYP1A2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1827415-B1 | CYCLOPROPANE ACID DERIVATIVES FOR THE REDUCTION OF LIPID LEVELS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-01-20 | — | — | EP | disclosed |