Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 9/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220407 | 0.81 | CTSK (0.44) | CA1CA7CA2CTSKCTSS | |
| SCHEMBL9220413 | 0.81 | CTSK (0.44) | CA1CA7CA2CTSKCTSS | |
| SCHEMBL28584587 | 0.81 | CA1 (0.47) | CA1CA7CA2CTSKCTSS | |
| SCHEMBL28525464 | 0.75 | CA1 (0.38) | CA1CA7CA2CTSKCTSS | |
| SCHEMBL20415389 | 0.73 | CA1 (0.40) | CA1CA7CA2CTSKCTSS | |
| SCHEMBL240769 | 0.72 | CA1 (0.42) | CA1CA7CA2CTSKCTSS | |
| SCHEMBL29873876 | 0.71 | MEN1 (0.44) | CA1CA7CA2CTSKCTSS | |
| SCHEMBL22605368 | 0.71 | CA1 (0.49) | CA1CA7CA2CTSKCTSS | |
| SCHEMBL16730545 | 0.71 | MEN1 (0.44) | CA1CA7CA2CTSKCTSS | |
| SCHEMBL28170911 | 0.71 | CA1 (0.41) | CA1CA7CA2CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735400-B | Cyclic sulfamoyl arylamide derivatives and their use as medicaments for the treatment of hepatitis B | 爱尔兰詹森科学公司 | 2021-02-02 | — | — | CN | disclosed |