Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.44 |
| ▸ | CTSS | P25774 | 6/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220413 | 1.00 | CTSK (0.44) | CTSKCTSSCA1CA7CA2 | |
| SCHEMBL28243508 | 0.83 | CA1 (0.42) | CTSKCTSSCA1CA7CA2 | |
| SCHEMBL28519064 | 0.81 | CA1 (0.41) | CTSKCTSSCA1CA7CA2 | |
| SCHEMBL11059855 | 0.79 | CTSK (0.47) | CTSKCTSSCA1CA7CA2 | |
| SCHEMBL28525464 | 0.78 | CA1 (0.38) | CTSKCTSSCA1CA7CA2 | |
| SCHEMBL14779117 | 0.76 | CTSK (0.45) | CTSKCTSSCA1CA7CA2 | |
| SCHEMBL5861940 | 0.76 | HSD17B10 (0.41) | CA1CA7CA2MEN1GAA | |
| SCHEMBL4246389 | 0.76 | CA1 (0.42) | CTSKCTSSCA1CA7CA2 | |
| SCHEMBL28898391 | 0.76 | CA1 (0.42) | CTSKCTSSCA1CA7CA2 | |
| SCHEMBL9424992 | 0.76 | CA1 (0.42) | CTSKCTSSCA1CA7CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378690-A | Treatment of angiotensin induced hypertension | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |