Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21606032 | 0.86 | FAAH (0.45) | FAAHKMT2AGABRPGABRDGABRA1 | |
| SCHEMBL21605578 | 0.78 | FAAH (0.45) | FAAHKMT2AGABRPGABRDGABRA1 | |
| SCHEMBL21607433 | 0.77 | FAAH (0.44) | FAAHKMT2AGABRG2GABRB3GABRA5 | |
| SCHEMBL21605983 | 0.77 | FAAH (0.42) | FAAHKMT2AGABRPGABRDGABRA1 | |
| SCHEMBL21607874 | 0.76 | FAAH (0.45) | FAAHKMT2AGABRG2GABRB3GABRA5 | |
| SCHEMBL21605634 | 0.76 | FAAH (0.43) | FAAHKMT2AGABRPGABRDGABRA1 | |
| SCHEMBL21605664 | 0.75 | FAAH (0.42) | FAAHKMT2AMEN1NPC1RAB9A | |
| SCHEMBL21598388 | 0.75 | MARS1 (0.47) | FAAHKMT2AGABRA2GABRB2GAA | |
| SCHEMBL21607519 | 0.75 | FAAH (0.59) | FAAHKMT2AGABRA2GABRB2MEN1 | |
| SCHEMBL21607427 | 0.74 | FAAH (0.44) | FAAHKMT2AGAAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112292183-A | 6-aminopyridin-3-yl-pyrazoles as modulators of ROR γ t | 詹森药业有限公司 | 2021-01-29 | — | — | CN | disclosed |