Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27987313 | 0.94 | ALDH1A1 (0.31) | L3MBTL1 | |
| Urea SCHEMBL28287663 | 0.90 | CA1 (0.31) | — | |
| Benzene SCHEMBL27824069 | 0.89 | MAPT (0.32) | — | |
| SCHEMBL293657 | 0.89 | — | — | |
| SCHEMBL27991715 | 0.89 | CA1 (0.31) | — | |
| Bicarbonate SCHEMBL23500108 | 0.88 | CA2 (0.35) | KDM4EALOX15 | |
| Urea SCHEMBL28281517 | 0.88 | CA1 (0.31) | — | |
| Lactic Acid SCHEMBL29169375 | 0.87 | TP53 (0.38) | ALOX15 | |
| Bromide SCHEMBL557295 | 0.87 | — | — | |
| Ammonia Solution, Strong SCHEMBL28215623 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321399-B | Preparation method of chemical intermediate | 漯河豫博生物化工有限公司 | 2022-10-18 | — | — | CN | claimed |
| CN-112299968-B | Preparation method of chemical raw material | 广州彼西络科技有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-112479838-A | Application of imidazole carbonate in preparation of chemical intermediates | 山东卓俊实业有限公司 | 2021-03-12 | — | — | CN | claimed |
| CN-112321399-A | Preparation method of chemical intermediate | 山东卓俊实业有限公司 | 2021-02-05 | — | — | CN | claimed |
| CN-112299968-A | Preparation method of chemical raw material | 山东卓俊实业有限公司 | 2021-02-02 | — | — | CN | claimed |
| CN-111117594-B | Electrochromic material and electrochromic device based on dynamic metal-ligand complexation | 吉林大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-112321399-B | Preparation method of chemical intermediate | 漯河豫博生物化工有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-112299968-B | Preparation method of chemical raw material | 广州彼西络科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-112479838-A | Application of imidazole carbonate in preparation of chemical intermediates | 山东卓俊实业有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-112321399-A | Preparation method of chemical intermediate | 山东卓俊实业有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-112299968-A | Preparation method of chemical raw material | 山东卓俊实业有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-112299969-A | Application of imidazole carbonate in preparation of important chemical raw materials | 山东卓俊实业有限公司 | 2021-02-02 | — | — | CN | disclosed |