SCHEMBL2851964

SCHEMBL2851964

CC1(COCC(F)(F)C(F)(F)C(F)(F)F)COC1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3846933 0.93 EPHX1 (0.35) EPHX1
SCHEMBL3689299 0.89 EPHX1 (0.40) EPHX1
SCHEMBL3849142 0.83
SCHEMBL8862815 0.83 EPHX1 (0.35) EPHX1
SCHEMBL2798388 0.81 EPHX1 (0.38) EPHX1
SCHEMBL5668867 0.79
SCHEMBL5666703 0.79
SCHEMBL4330354 0.78 EPHX1 (0.34) EPHX1
SCHEMBL15195266 0.78 EPHX1 (0.40) EPHX1
SCHEMBL31544800 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7148309-B2 Amorphous polyether glycols based on bis-substituted oxetane monomers AMPAC FINE CHEMICALS LLC (US) 2006-12-12 US claimed
US-20060135729-A1 Amorphous polyether glycols based on bis-substituted oxetane monomers AEROJET-GENERAL CORPORATION (US) 2006-06-22 US claimed
US-6998460-B2 Amorphous polyether glycols based on bis-substituted oxetane and tetrahydrofuran monomers AEROJET-GENERAL CORPORATION (US) 2006-02-14 US claimed
US-20050154217-A1 Amorphous polyether glycols based on bis-substituted oxetane and tetrahydrofuran monomers AEROJET-GENERAL CORPORATION 2005-07-14 US claimed
US-6891013-B1 Fluorinated polyurethane elastomers prepared from polyether prepolymers formed from mono-substituted fluorinated oxetane monomers and tetrahydrofuran AEROJET-GENERAL CORPORATION (US) 2005-05-10 US claimed
US-6825316-B2 FOR MAKING A FLUORINATED POLYETHERURETHANE COPOLYMER ELASTOMER; TEFLON SIMILAR NONSTICK COATINGS, HYDROPHOBIC, LOW SURFACE ENERGIES, LOW GLASS TRANSITION TEMPERATURES, NONABRASIVE AND TEAR STRENGTH, ADHESION AEROJET-GENERAL CORPORATION 2004-11-30 US claimed
US-20040087759-A1 Fluorinated thermoset polyurethane elastomers prepared from polyether prepolymers formed mono-substituted fluorinated oxetane monomers AEROJET ROCKETDYNE, INC. (F/K/A AEROJET-GENERAL CORPORATION) 2004-05-06 US claimed
US-20030158373-A1 Amorphous polyether glycols based on bis-substituted oxetane monomers AEROJET-GENERAL CORPORATION (US) 2003-08-21 US claimed
US-6479623-B1 Amorphous polyether glycols based on bis-substituted oxetane monomers OMNOVA SOLUTIONS, INC, 2002-11-12 US claimed
US-6448368-B1 HYDROXY TERMINATED POLYETHERS HAVING ASYMMETRIC PENDANT ALKOXYMETHYLENE GROUPS; HYDROPHOBIC; PREPARATION OF POLYURETHANE ELASTOMERS, THERMOSET PLASTICS AND COATINGS AEROJET-GENERAL CORPORATION 2002-09-10 US claimed
EP-1228121-A1 AMORPHOUS POLYETHER GLYCOLS BASED ON BIS-SUBSTITUTED OXETANE MONOMERS Aerojet-General Corporation (US) 2002-08-07 EP claimed
US-6417314-B1 WEAR RESISTANCE, TEAR AND BONDING STRENGTH; COATINGS, PLASTICS AEROJET-GENERAL CORPORATION 2002-07-09 US claimed
US-6380351-B1 FLUORINATED POLYETHERS AEROJET-GENERAL CORPORATION 2002-04-30 US claimed
WO-2001005871-A1 AMORPHOUS POLYETHER GLYCOLS BASED ON BIS-SUBSTITUTED OXETANE MONOMERS AEROJET-GENERAL CORPORATION (US) 2001-01-25 WO claimed
US-5807977-A Polyoxetanes based on pendant perfluoroalkyl side chains such as 3-methyl-3-(2,2,2-trifluoroethoxymethyl)-oxetane to form polyethers; very low surface energy, high hydrophobicity, low glass transition temperature and low coefficient of friction AEROJET GENERAL CORPORATION (US) 1998-09-15 US claimed
US-5668251-A Preparation of co-prepolymers from mono-substituted fluorinated monomers and tetrahydrofuran AEROJET-GENERAL CORPORATION (US) 1997-09-16 US claimed
US-5654450-A THERMOPLASTIC RESIN INTERMEDIATES; TEAR STRENGTH, ADHESION AEROJET-GENERAL CORPORATION (US) 1997-08-05 US claimed
US-5650483-A PREPARING A SOLUTION OF A CATALYST, AN INITIATOR AND A SOLVENT, CONTACTING SOLUTION WITH A SECOND SOLUTION CONTAINING FLUORINATED OXETANE MONOMER(S) AND CONTROLLING THE TEMPERATURE OF THE MIXTURE AEROJET-GENERAL CORPORATION (US) 1997-07-22 US claimed
WO-1996021657-A1 MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS AEROJET-GENERAL CORPORATION (US) 1996-07-18 WO claimed
EP-2197678-B1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2013-11-06 EP disclosed
EP-1389224-B1 POLYMERIC SURFACTANTS DERIVED FROM CYCLIC MONOMERS HAVING PENDANT FLUORINATED CARBON GROUPS OMNOVA SOLUTIONS INC (US) 2010-01-13 EP disclosed
WO-2009047112-A1 A LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2009-04-16 WO disclosed
EP-2047988-A1 A lithographic printing plate precursor Agfa Graphics N.V. (BE) 2009-04-15 EP disclosed
US-7354985-B2 Fluorinated thermoset polyurethane elastomers prepared from polyether prepolymers formed from mono-substituted fluorinated oxetane monomers AEROJET ROCKETDYNE, INC. (F/K/A AEROJET-GENERAL CORPORATION) 2008-04-08 US disclosed
US-7320829-B2 Fluorinated polymer and amine resin compositions and products formed therefrom OMNOVA SOLUTIONS INC. (US) 2008-01-22 US disclosed
US-7148309-B2 Amorphous polyether glycols based on bis-substituted oxetane monomers AMPAC FINE CHEMICALS LLC (US) 2006-12-12 US disclosed
EP-0811004-B1 MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS AEROJET GENERAL CO (US) 2006-12-06 EP disclosed
EP-1297047-B1 ANIONIC WATERBORNE POLYURETHANE DISPERSIONS CONTAINING POLYFLUOROOXETANES OMNOVA SOLUTIONS INC (US) 2006-11-15 EP disclosed
EP-1244727-B1 MONOHYDRIC POLYFLUOROOXETANE OLIGOMERS, POLYMERS, AND COPOLYMERS AND COATINGS CONTAINING THE SAME OMNOVA SOLUTIONS INC (US) 2006-08-09 EP disclosed
US-7087710-B2 Polymeric surfactants derived from cyclic monomers having pendant fluorinated carbon groups OMNOVA SOLUTIONS INC. (US) 2006-08-08 US disclosed
US-20060135729-A1 Amorphous polyether glycols based on bis-substituted oxetane monomers AEROJET-GENERAL CORPORATION (US) 2006-06-22 US disclosed
US-7022801-B2 Polymeric surfactants derived from cyclic monomers having pendant fluorinated carbon groups OMNOVA SOLUTIONS INC. (US) 2006-04-04 US disclosed
US-6998460-B2 Amorphous polyether glycols based on bis-substituted oxetane and tetrahydrofuran monomers AEROJET-GENERAL CORPORATION (US) 2006-02-14 US disclosed
US-6962966-B2 Monohydric polyfluorooxetane oligomers, polymers, and copolymers and coatings containing the same OMNOVA SOLUTIONS INC. (US) 2005-11-08 US disclosed
US-6927276-B2 Monohydric polyfluorooxetane oligomers, polymers, and copolymers and coating containing the same OMNOVA SOLUTIONS INC. (US) 2005-08-09 US disclosed
US-20050154217-A1 Amorphous polyether glycols based on bis-substituted oxetane and tetrahydrofuran monomers AEROJET-GENERAL CORPORATION 2005-07-14 US disclosed
US-6891013-B1 Fluorinated polyurethane elastomers prepared from polyether prepolymers formed from mono-substituted fluorinated oxetane monomers and tetrahydrofuran AEROJET-GENERAL CORPORATION (US) 2005-05-10 US disclosed
US-20040242804-A1 Polymeric surfactants derived from cyclic monomers having pendant fluorinated carbon groups OMNOVA SOLUTIONS INC. 2004-12-02 US disclosed
US-6825316-B2 FOR MAKING A FLUORINATED POLYETHERURETHANE COPOLYMER ELASTOMER; TEFLON SIMILAR NONSTICK COATINGS, HYDROPHOBIC, LOW SURFACE ENERGIES, LOW GLASS TRANSITION TEMPERATURES, NONABRASIVE AND TEAR STRENGTH, ADHESION AEROJET-GENERAL CORPORATION 2004-11-30 US disclosed
US-20040224164-A1 Fluorinated polymer and amine resin compositions and products formed therefrom OMNOVA SOLUTIONS INC. 2004-11-11 US disclosed
US-20040087759-A1 Fluorinated thermoset polyurethane elastomers prepared from polyether prepolymers formed mono-substituted fluorinated oxetane monomers AEROJET ROCKETDYNE, INC. (F/K/A AEROJET-GENERAL CORPORATION) 2004-05-06 US disclosed
US-20040048957-A1 Polymeric surfactants derived from cyclic monomers having pendant fluorinated carbon groups OMNOVA SOLUTIONS INC. 2004-03-11 US disclosed
EP-1389224-A2 POLYMERIC SURFACTANTS DERIVED FROM CYCLIC MONOMERS HAVING PENDANT FLUORINATED CARBON GROUPS Omnova Soltions Inc (US) 2004-02-18 EP disclosed
US-6686051-B1 CLEANABLE STAIN AND WEAR RESISTANCE DRY ERASE LAMINIATES; AMINO RESIN CURED BLOCK PERFLUORO- SUBSTITUTED POLYETHER REACTED WITH DIBASIC ACID OMNOVA SOLUTIONS INC. 2004-02-03 US disclosed
US-6660828-B2 Powder coating; fluorinated polyoxetanes; addition-condensation copolymer OMNOVA SOLUTIONS INC. 2003-12-09 US disclosed
US-20030208015-A1 Monohydric polyfluorooxetane oligomers, polymers, and copolymers and coatings containing the same OMNOVA SOLUTIONS INC. 2003-11-06 US disclosed
US-20030158373-A1 Amorphous polyether glycols based on bis-substituted oxetane monomers AEROJET-GENERAL CORPORATION (US) 2003-08-21 US disclosed
US-20030149186-A1 Monohydric polyfluorooxetane oligomers, polymers, and copolymers and coating containing the same OMNOVA SOLUTIONS INC 2003-08-07 US disclosed
US-20030138650-A1 Polyester coetherified melamine formaldehyde copolymers OMNOVA SOLUTIONS INC. 2003-07-24 US disclosed
US-6579966-B1 Copolymers of perfluoroalkyl containing polyethers with polycarboxylic acids and cured with amino resins; laminates with improved cleanable stain resistance OMNOVA SOLUTIONS INC. 2003-06-17 US disclosed
US-20030109662-A1 Polymeric surfactants derived from cyclic monomers having pendant fluorinated carbon groups DEUTSCHE BANK TRUST COMPANY AMERICAS 2003-06-12 US disclosed
US-20030092862-A1 Fluorinated short carbon atom side chain and polar group containing polymer, and flow, or leveling, or wetting agents thereof OMNOVA SOLUTIONS INC. 2003-05-15 US disclosed
EP-1297047-A2 ANIONIC WATERBORNE POLYURETHANE DISPERSIONS CONTAINING POLYFLUOROOXETANES OMNOVA SOLUTIONS INC. (US) 2003-04-02 EP disclosed
WO-2002092660-A2 POLYMERIC SURFACTANTS DERIVED FROM CYCLIC MONOMERS HAVING PENDANT FLUORINATED CARBON GROUPS OMNOVA SOLTIONS INC (US) 2002-11-21 WO disclosed
US-6479623-B1 Amorphous polyether glycols based on bis-substituted oxetane monomers OMNOVA SOLUTIONS, INC, 2002-11-12 US disclosed
US-6465566-B2 REPEAT UNIT DERIVED FROM A HYDROXYL CONTAINING CARBOXYLIC ACID DISPERSANT OMNOVA SOLUTIONS INC. 2002-10-15 US disclosed
EP-1244727-A1 MONOHYDRIC POLYFLUOROOXETANE OLIGOMERS, POLYMERS, AND COPOLYMERS AND COATINGS CONTAINING THE SAME OMNOVA SOLUTIONS INC. (US) 2002-10-02 EP disclosed
US-20020127420-A1 Two stage thermoformable fluorinated polyoxetane-polyester copolymers DEUTSCHE BANK TRUST COMPANY AMERICAS 2002-09-12 US disclosed
US-6448368-B1 HYDROXY TERMINATED POLYETHERS HAVING ASYMMETRIC PENDANT ALKOXYMETHYLENE GROUPS; HYDROPHOBIC; PREPARATION OF POLYURETHANE ELASTOMERS, THERMOSET PLASTICS AND COATINGS AEROJET-GENERAL CORPORATION 2002-09-10 US disclosed
EP-1228121-A1 AMORPHOUS POLYETHER GLYCOLS BASED ON BIS-SUBSTITUTED OXETANE MONOMERS Aerojet-General Corporation (US) 2002-08-07 EP disclosed
US-6417314-B1 WEAR RESISTANCE, TEAR AND BONDING STRENGTH; COATINGS, PLASTICS AEROJET-GENERAL CORPORATION 2002-07-09 US disclosed
WO-2002034848-A1 CURED POLYESTERS CONTAINING FLUORINATED SIDE CHAINS OMNOVA SOLUTIONS INC. (US) 2002-05-02 WO disclosed
US-6380351-B1 FLUORINATED POLYETHERS AEROJET-GENERAL CORPORATION 2002-04-30 US disclosed
WO-2002004538-A2 ANIONIC WATERBORNE POLYURETHANE DISPERSIONS CONTAINING POLYFLUOROOXETANES OMNOVA SOLUTIONS INC. (US) 2002-01-17 WO disclosed
WO-2001048051-A1 MONOHYDRIC POLYFLUOROOXETANE OLIGOMERS, POLYMERS, AND COPOLYMERS AND COATINGS CONTAINING THE SAME OMNOVA SOLUTIONS, INC. (US) 2001-07-05 WO disclosed
WO-2001005871-A1 AMORPHOUS POLYETHER GLYCOLS BASED ON BIS-SUBSTITUTED OXETANE MONOMERS AEROJET-GENERAL CORPORATION (US) 2001-01-25 WO disclosed
US-6037483-A CHARGING REACTION VESSEL WITH AQUEOUS MIXTURE OF MONO-SUBSTITURED OXETANE, FLUOROALCOHOL, PHASE TRANSFER CATALYST AND STRONG BASE TO FORM REACTION MIXTURE; HEATING UNTIL REACTION IS COMPLETE AEROJET-GENERAL CORPORATION (US) 2000-03-14 US disclosed
EP-0811004-A4 MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS AEROJET GENERAL CO (US) 1998-09-30 EP disclosed
US-5807977-A Polyoxetanes based on pendant perfluoroalkyl side chains such as 3-methyl-3-(2,2,2-trifluoroethoxymethyl)-oxetane to form polyethers; very low surface energy, high hydrophobicity, low glass transition temperature and low coefficient of friction AEROJET GENERAL CORPORATION (US) 1998-09-15 US disclosed
US-5703194-A WATERPROOFING; TEAR STRENGTH; BONDING STRENGTH AEROJET-GENERAL CORPORATION (US) 1997-12-30 US disclosed
EP-0811004-A1 MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS AEROJET-GENERAL CORPORATION (US) 1997-12-10 EP disclosed
US-5674951-A POLYETHERURETHANE COATINGS USING GLYCOL MONOMERS WITH -CH2-O-CH2-RF PENDANT GROUPS; MOLDING MATERIALS; PROTECTION FOR GLASS-RUN CHANNEL, E.G. AUTOMOBILE WINDOWS GENCORP INC. (US) 1997-10-07 US disclosed
US-5668250-A Polyether coprepolymers formed from mono-substituted fluorinated oxetane monomers and tetrahydrofuran AEROJET-GENERAL CORPORATION (US) 1997-09-16 US disclosed
US-5668251-A Preparation of co-prepolymers from mono-substituted fluorinated monomers and tetrahydrofuran AEROJET-GENERAL CORPORATION (US) 1997-09-16 US disclosed
US-5654450-A THERMOPLASTIC RESIN INTERMEDIATES; TEAR STRENGTH, ADHESION AEROJET-GENERAL CORPORATION (US) 1997-08-05 US disclosed
US-5650483-A PREPARING A SOLUTION OF A CATALYST, AN INITIATOR AND A SOLVENT, CONTACTING SOLUTION WITH A SECOND SOLUTION CONTAINING FLUORINATED OXETANE MONOMER(S) AND CONTROLLING THE TEMPERATURE OF THE MIXTURE AEROJET-GENERAL CORPORATION (US) 1997-07-22 US disclosed
US-5637772-A OIL REPELLENT COATINGS; ANTIFOULING AGENTS; RELEASE AGENTS; ENCAPSULATION OF ELECTRICAL DEVICES; CURING AGENT FOR EPOXIDES AEROJET GENERAL CORPORATION (US) 1997-06-10 US disclosed
WO-1996021657-A1 MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS AEROJET-GENERAL CORPORATION (US) 1996-07-18 WO disclosed
WO-1996021657-A1 MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS AEROJET-GENERAL CORPORATION (US) 1996-07-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050154217-A1 Amorphous polyether glycols based on bis-substituted oxetane and tetrahydrofuran monomers GNE, PFAS, FTO EPHX1 1913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.