SCHEMBL28519699

SCHEMBL28519699

CC(O)COc1ccc(-c2cccc3c2Cc2ccccc2-3)cc1C(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 6/20 0.35
ADRB1 P08588 6/20 0.35
ADRB3 P13945 6/20 0.35
LMNA P02545 1/20 0.35
PNMT P11086 1/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TLR4 O00206 1/20 0.33
FFAR1 O14842 2/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32
CTSA P10619 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28973513 0.88 PTPRC (0.41) PNMTNPC1RAB9AMEN1KMT2A
SCHEMBL28348127 0.87 KMT2A (0.36) ADRB2ADRB1ADRB3LMNAPNMT
SCHEMBL576757 0.87 KCNH2 (0.38) ADRB2LMNAPNMTNPC1RAB9A
SCHEMBL28525858 0.84 USP2 (0.36) ADRB2ADRB1ADRB3LMNAPNMT
SCHEMBL28537847 0.81 SLC6A9 (0.43) CYP2D6PRMT5WDR77
SCHEMBL2806274 0.81 LMNA (0.50) ADRB2ADRB1ADRB3LMNAPNMT
SCHEMBL28696289 0.78 LMNA (0.40) ADRB2ADRB1ADRB3LMNAPNMT
SCHEMBL30215904 0.78 PTPRC (0.41) LMNAPNMTNPC1RAB9AMEN1
SCHEMBL30493148 0.78 LMNA (0.44) LMNAPNMTNPC1RAB9AMEN1
SCHEMBL31121331 0.78 HSP90AA1 (0.42) LMNAPNMTNPC1RAB9ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109071789-B Polycarbonate copolymer, optical lens and film using same, and method for producing same 三菱瓦斯化学株式会社 2021-01-15 CN disclosed