Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.55 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 2/20 | 0.48 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5621838 | 0.81 | MEN1 (0.76) | MEN1KMT2AHPGDKDM4ELMNA | |
| SCHEMBL3486077 | 0.80 | MTNR1A (0.62) | MEN1KMT2AHPGDKDM4ELMNA | |
| SCHEMBL11186472 | 0.80 | NR4A1 (0.63) | MEN1KMT2AHPGDKDM4ELMNA | |
| SCHEMBL29388082 | 0.79 | ALDH1A1 (0.58) | MEN1KMT2AHPGDKDM4ELMNA | |
| SCHEMBL7217415 | 0.79 | NQO2 (0.56) | MEN1KMT2AHPGDKDM4ELMNA | |
| SCHEMBL11382923 | 0.78 | HPGD (0.59) | MEN1KMT2AHPGDKDM4ELMNA | |
| SCHEMBL8689214 | 0.78 | ALDH1A1 (0.79) | MEN1KMT2AHPGDKDM4ELMNA | |
| SCHEMBL28605598 | 0.77 | KMT2A (1.00) | MEN1KMT2AHPGDKDM4ELMNA | |
| SCHEMBL1147050 | 0.77 | CDC25B (0.71) | MEN1KMT2AHPGDKDM4ELMNA | |
| SCHEMBL30519263 | 0.77 | CDC25B (0.71) | MEN1KMT2AHPGDKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112262121-A | Novel process for the preparation of tapentadol | 法尔玛赞公司 | 2021-01-22 | — | — | CN | disclosed |