Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13180253 | 0.81 | HDAC6 (0.52) | HDAC6HDAC1MTNR1AHDAC3HDAC4 | |
| SCHEMBL24718828 | 0.81 | MTNR1A (0.59) | HDAC6HDAC1MTNR1AHDAC3HDAC4 | |
| SCHEMBL4509202 | 0.75 | HDAC6 (0.46) | HDAC6HDAC1MTNR1AHDAC3HDAC4 | |
| SCHEMBL7711222 | 0.75 | MTNR1A (0.44) | HDAC6HDAC1MTNR1AHDAC3HDAC4 | |
| SCHEMBL13102183 | 0.74 | MTNR1A (0.62) | HDAC6HDAC1MTNR1AALDH1A1KMT2A | |
| SCHEMBL1450283 | 0.73 | ALDH1A1 (0.68) | ALDH1A1KMT2AUSP2CHRM2CHRM4 | |
| SCHEMBL29555396 | 0.73 | ALDH1A1 (0.68) | ALDH1A1KMT2AUSP2CHRM2CHRM4 | |
| SCHEMBL11485140 | 0.71 | HTR2A (0.44) | HDAC6HDAC1MTNR1AHDAC3HDAC4 | |
| SCHEMBL28320602 | 0.71 | HDAC6 (0.46) | HDAC6HDAC1MTNR1AHDAC3HDAC4 | |
| SCHEMBL22736718 | 0.71 | MTNR1A (0.54) | HDAC6HDAC1MTNR1AHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112423758-A | Adenosine receptor binding compounds | 尼康治疗公司 | 2021-02-26 | — | — | CN | disclosed |