Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6360338 | 0.91 | MAPT (0.67) | MAPTGAASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL24590212 | 0.86 | MAPT (0.65) | MAPTGAASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL1003426 | 0.86 | SMN1; SMN2 (0.64) | GAASMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL24202306 | 0.81 | MAPT (0.56) | MAPTGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6359507 | 0.81 | KDM4E (0.65) | MAPTGAASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL18902272 | 0.80 | L3MBTL1 (0.71) | MAPTSMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL3827918 | 0.79 | GAA (0.82) | MAPTGAASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8437113 | 0.79 | KDM4E (0.71) | MAPTGAASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL1004117 | 0.79 | KMT2A (0.59) | MAPTGAASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL2914113 | 0.79 | SMN1; SMN2 (0.79) | SMN1; SMN2ALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104761420-B | Method for synthesizing amide from methyl aromatic hydrocarbon and amine in water phase | 江西师范大学 | 2021-03-05 | — | — | CN | disclosed |