SCHEMBL28520202

SCHEMBL28520202

CCC(C(=O)N1CCCC[C@@]1(C(=O)O)C(CCc1ccc(OC)c(OC)c1)c1cccc(OCC(=O)OC(C)(C)C)c1)c1cc(OC)c(OC)c(OC)c1

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 13/20 0.54
FKBP5 Q13451 7/20 0.48
FKBP4 Q02790 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28515932 0.86 FKBP1A (0.49) FKBP1AFKBP5FKBP4
SCHEMBL29827870 0.82 FKBP1A (0.47) FKBP1AFKBP5FKBP4
SCHEMBL18086954 0.78 FKBP1A (0.84) FKBP1AFKBP5FKBP4
SCHEMBL609095 0.76 FKBP1A (0.50) FKBP1AFKBP5FKBP4
SCHEMBL609094 0.76 FKBP1A (0.50) FKBP1AFKBP5FKBP4
SCHEMBL611146 0.74 FKBP1A (0.53) FKBP1AFKBP5FKBP4
SCHEMBL611147 0.74 FKBP1A (0.53) FKBP1AFKBP5FKBP4
SCHEMBL29827767 0.73 FKBP1A (0.40) FKBP1AFKBP5
SCHEMBL15049104 0.72 FKBP1A (0.46) FKBP1AFKBP5FKBP4
SCHEMBL16158169 0.72 FKBP1A (0.46) FKBP1AFKBP5FKBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112409376-A Protein degradation targeting chimera based on DCAF15, and preparation method and application thereof 华东师范大学 2021-02-26 CN disclosed