Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | TSHR | P16473 | 5/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL1626507 | 1.00 | ALDH1A1 (0.73) | ALDH1A1TSHRSMN1; SMN2DNM1LMNA | |
| Monoethanolamine SCHEMBL4258627 | 1.00 | — | — | |
| Monoethanolamine SCHEMBL5312187 | 0.96 | — | — | |
| Monoethanolamine SCHEMBL4218260 | 0.96 | ALDH1A1 (0.67) | ALDH1A1TSHRSMN1; SMN2DNM1LMNA | |
| Monoethanolamine SCHEMBL3108725 | 0.96 | ALDH1A1 (0.67) | ALDH1A1TSHRSMN1; SMN2DNM1LMNA | |
| Monoethanolamine SCHEMBL28112205 | 0.92 | — | — | |
| Monoethanolamine SCHEMBL5730563 | 0.91 | — | — | |
| Propylamine SCHEMBL327066 | 0.87 | ALDH1A1 (0.67) | ALDH1A1TSHRSMN1; SMN2DNM1LMNA | |
| Propanol SCHEMBL2322073 | 0.87 | — | — | |
| Propanol SCHEMBL1134197 | 0.87 | ALDH1A1 (0.67) | ALDH1A1TSHRSMN1; SMN2DNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142833-B1 | Molecular sieves | DALIAN CHEMICAL PHYSICS INST (CN) | 2010-01-13 | — | — | EP | disclosed |
| EP-0801329-B1 | RADIATION-SENSITIVE COMPOSITION AND RECORDING MEDIUM PRODUCED THEREFROM | CLARIANT FINANCE BVI LTD (VG) | 2002-03-27 | — | — | EP | disclosed |
| EP-1142833-A1 | Molecular sieves | DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2001-10-10 | — | — | EP | disclosed |
| US-6110639-A | Radiation-sensitive composition and recording medium using the same | HOECHST JAPAN LIMITED (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0801329-A1 | RADIATION-SENSITIVE COMPOSITION AND RECORDING MEDIUM PRODUCED THEREFROM | HOECHST JAPAN LIMITED (JP) | 1997-10-15 | — | — | EP | disclosed |