Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906903 | 0.84 | PTPN11 (0.41) | PTPN11 | |
| SCHEMBL28524841 | 0.83 | — | — | |
| SCHEMBL23064027 | 0.83 | CNR1 (0.31) | KIF18AAVPR1ACNR2 | |
| SCHEMBL30809736 | 0.81 | RET (0.38) | KIF18ACNR2 | |
| SCHEMBL23126467 | 0.81 | RET (0.38) | KIF18ACNR2 | |
| SCHEMBL30809735 | 0.81 | RET (0.38) | KIF18ACNR2 | |
| SCHEMBL28517929 | 0.81 | — | — | |
| SCHEMBL28945530 | 0.73 | PTPN11 (0.32) | PTPN11CNR2 | |
| SCHEMBL28793472 | 0.71 | PTPN11 (0.36) | PTPN11CNR2 | |
| SCHEMBL29097721 | 0.70 | HCRTR2 (0.38) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112351780-B | Substituted heterocyclic inhibitors of PTPN11 | 纳维尔制药有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-112351780-A | Substituted heterocyclic inhibitors of PTPN11 | 纳维尔制药有限公司 | 2021-02-09 | — | — | CN | disclosed |