Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28793472 | 0.91 | PTPN11 (0.36) | PTPN11PIK3CAMTORCNR2MEN1 | |
| SCHEMBL23500876 | 0.85 | CNR2 (0.35) | PIK3CACNR2 | |
| SCHEMBL28793458 | 0.80 | KDM4E (0.38) | PTPN11ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL20399762 | 0.80 | HDAC3 (0.33) | PTPN11PIK3CAMTORCNR2ALDH1A1 | |
| SCHEMBL28906903 | 0.79 | PTPN11 (0.41) | PTPN11PIK3CAMTORSCN10A | |
| SCHEMBL28793429 | 0.78 | KDM4E (0.36) | PTPN11CNR2ALDH1A1KDM4ETDP1 | |
| SCHEMBL23500914 | 0.76 | P2RX7 (0.42) | PTPN11 | |
| SCHEMBL20399737 | 0.76 | RET (0.41) | PIK3CACNR2 | |
| SCHEMBL30561170 | 0.76 | RET (0.41) | PIK3CACNR2 | |
| SCHEMBL29070211 | 0.74 | PTPN11 (0.41) | PTPN11CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829362-A | Six-membered and five-membered aromatic ring derivative containing nitrogen heteroatom and used as SHP2 inhibitor | 成都倍特药业股份有限公司 | 2022-07-29 | — | — | CN | disclosed |