Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1694515 | 0.94 | BCL2 (0.48) | BCL2BCL2L1MCL1P2RX7LIPG | |
| SCHEMBL9210068 | 0.86 | BCL2 (0.46) | BCL2BCL2L1MCL1P2RX7LIPG | |
| SCHEMBL30035793 | 0.85 | BCL2 (0.39) | BCL2BCL2L1MCL1P2RX7LIPG | |
| SCHEMBL6017718 | 0.80 | BCL2 (0.47) | BCL2BCL2L1MCL1P2RX7LIPG | |
| SCHEMBL28520572 | 0.79 | BCL2 (0.41) | BCL2BCL2L1MCL1P2RX7LIPG | |
| SCHEMBL13537421 | 0.78 | BCL2 (0.46) | BCL2BCL2L1MCL1P2RX7LIPG | |
| SCHEMBL26685781 | 0.78 | MEN1 (0.40) | BCL2BCL2L1MCL1P2RX7KDM4E | |
| Carbamic Acid SCHEMBL28131089 | 0.78 | TPMT (0.57) | KDM4ETPMTCYP1A2CYP3A4TSHR | |
| Carbamic Acid SCHEMBL28102259 | 0.78 | LMNA (0.44) | LMNAKDM4ETPMTCYP1A2CYP3A4 | |
| Carbamic Acid SCHEMBL28155281 | 0.76 | TPMT (0.60) | KDM4ETPMTCYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112312909-A | Compounds for the treatment of kinase-dependent disorders | 埃克塞里艾克西斯公司 | 2021-02-02 | — | — | CN | disclosed |