Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.77 |
| ▸ | ARG2 | P78540 | 4/20 | 0.48 |
| ▸ | ARG1 | P05089 | 3/20 | 0.48 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 5/20 | 0.43 |
| ▸ | NOS1 | P29475 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL6561904 | 0.91 | GSR (0.74) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL27645682 | 0.91 | GSR (0.74) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL5359221 | 0.90 | GSR (0.80) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28112654 | 0.89 | GSR (0.71) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28554653 | 0.89 | GSR (0.71) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28112652 | 0.89 | GSR (0.71) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL15053532 | 0.89 | GSR (0.71) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL19100135 | 0.89 | GSR (0.77) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL19100137 | 0.89 | GSR (0.77) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL28744335 | 0.88 | GSR (0.91) | GSRARG2ARG1RNPEPNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120053613-A | Application of multienzyme nano complex in preparation of medicines for treating cerebral apoplexy and cardiovascular diseases with other lactic acid metabolism abnormality | 上海市第四人民医院 | 2025-05-30 | — | — | CN | claimed |
| CN-116190911-A | High-heat-conductivity lithium ion battery diaphragm and preparation process thereof | 泰州衡川新能源材料科技有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-116190911-A | High-heat-conductivity lithium ion battery diaphragm and preparation process thereof | 泰州衡川新能源材料科技有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-112169025-A | Antibacterial medical instrument and preparation method thereof | 吉林大学第一医院 | 2021-01-05 | — | — | CN | disclosed |