Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.74 |
| ▸ | ARG2 | P78540 | 4/20 | 0.47 |
| ▸ | ARG1 | P05089 | 3/20 | 0.47 |
| ▸ | NOS2 | P35228 | 6/20 | 0.46 |
| ▸ | NOS1 | P29475 | 4/20 | 0.46 |
| ▸ | NOS3 | P29474 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL27645682 | 1.00 | GSR (0.74) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28112654 | 0.98 | GSR (0.71) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28112652 | 0.98 | GSR (0.71) | GSRARG2ARG1NOS2NOS1 | |
| Ornithine Aketoglutarate SCHEMBL2178954 | 0.94 | GSR (0.64) | GSRARG2ARG1NOS2NOS1 | |
| Ornithine Aketoglutarate SCHEMBL6512486 | 0.93 | GSR (0.62) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28520628 | 0.91 | GSR (0.77) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL5359221 | 0.89 | GSR (0.80) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL15053532 | 0.87 | GSR (0.71) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28554653 | 0.87 | GSR (0.71) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL7573653 | 0.87 | GSR (0.77) | GSRARG2ARG1NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119857170-A | Hydrogel with hemostatic and antioxidant properties and preparation method thereof | 广东海洋大学 | 2025-04-22 | — | — | CN | claimed |
| US-11912894-B2 | Antimicrobial and antifouling conformal hydrogel coatings | CORNELL UNIVERSITY (US) | 2024-02-27 | — | — | US | claimed |
| CN-117224732-A | Hydrogel with antibacterial and hemostatic functions and preparation method and application thereof | 广东海洋大学 | 2023-12-15 | — | — | CN | claimed |
| CN-113307743-A | Acrylamide-lysine adduct and preparation method and application thereof | 暨南大学 | 2021-08-27 | — | — | CN | claimed |
| US-20200172741-A1 | ANTIMICROBIAL AND ANTIFOULING CONFORMAL HYDROGEL COATINGS | CORNELL UNIVERSITY | 2020-06-04 | — | — | US | claimed |
| CN-117224732-B | Hydrogel with antibacterial and hemostatic functions and preparation method and application thereof | 广东海洋大学 | 2026-04-21 | — | — | CN | disclosed |
| CN-119857170-A | Hydrogel with hemostatic and antioxidant properties and preparation method thereof | 广东海洋大学 | 2025-04-22 | — | — | CN | disclosed |
| US-11912894-B2 | Antimicrobial and antifouling conformal hydrogel coatings | CORNELL UNIVERSITY (US) | 2024-02-27 | — | — | US | disclosed |
| CN-117224732-A | Hydrogel with antibacterial and hemostatic functions and preparation method and application thereof | 广东海洋大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-117224732-A | Hydrogel with antibacterial and hemostatic functions and preparation method and application thereof | 广东海洋大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-113307743-A | Acrylamide-lysine adduct and preparation method and application thereof | 暨南大学 | 2021-08-27 | — | — | CN | disclosed |
| CN-113307743-A | Acrylamide-lysine adduct and preparation method and application thereof | 暨南大学 | 2021-08-27 | — | — | CN | disclosed |
| CN-113307743-A | Acrylamide-lysine adduct and preparation method and application thereof | 暨南大学 | 2021-08-27 | — | — | CN | disclosed |
| US-20200172741-A1 | ANTIMICROBIAL AND ANTIFOULING CONFORMAL HYDROGEL COATINGS | CORNELL UNIVERSITY | 2020-06-04 | — | — | US | disclosed |
| CN-106267324-A | A kind of temperature response type macromolecule bio-medical adhesive and synthetic method thereof | 西北师范大学 | 2017-01-04 | — | — | CN | disclosed |
| JP-2004137382-A | WATER-ABSORBING COMPOSITION | EHIME PREFECTURE | 2004-05-13 | — | — | JP | disclosed |