Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30827513 | 0.87 | ALDH1A1 (0.78) | ALDH1A1MAPTKMT2ALMNAL3MBTL1 | |
| SCHEMBL1628833 | 0.87 | ALDH1A1 (0.78) | ALDH1A1MAPTKMT2ALMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8066446 | 0.85 | ALDH1A1 (0.76) | ALDH1A1MAPTKMT2ALMNAL3MBTL1 | |
| SCHEMBL29458655 | 0.85 | ALDH1A1 (0.76) | ALDH1A1MAPTKMT2ALMNAL3MBTL1 | |
| SCHEMBL3751183 | 0.85 | ALDH1A1 (0.74) | ALDH1A1MAPTKMT2ALMNAL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL27461059 | 0.85 | ALDH1A1 (0.76) | ALDH1A1MAPTKMT2ALMNAL3MBTL1 | |
| SCHEMBL10603067 | 0.85 | ALDH1A1 (0.67) | ALDH1A1MAPTKMT2ALMNAL3MBTL1 | |
| SCHEMBL27851778 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPTKMT2ALMNAL3MBTL1 | |
| SCHEMBL28309820 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MAPTKMT2ALMNAL3MBTL1 | |
| SCHEMBL31648307 | 0.81 | ALDH1A1 (0.71) | ALDH1A1MAPTKMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |