SCHEMBL28520840

SCHEMBL28520840

OC(COCc1ccco1)C[Se]c1c[nH]c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.45
HSD17B10 Q99714 2/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 6/20 0.40
LMNA P02545 3/20 0.40
HTT P42858 3/20 0.40
POLB P06746 4/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
GAA P10253 2/20 0.39
RECQL P46063 1/20 0.39
ESR2 Q92731 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP2C19 P33261 1/20 0.38
MAPT P10636 3/20 0.37
NPSR1 Q6W5P4 2/20 0.37
ALOX12 P18054 1/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
CA1 P00915 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28470747 0.77 CYP2D6 (0.56) CYP2D6HSD17B10TSHRKDM4EALDH1A1
SCHEMBL28214833 0.73 GPR84 (0.47) HSD17B10KDM4EALDH1A1POLBRECQL
SCHEMBL4620854 0.72 CYP2D6 (0.62) CYP2D6HSD17B10TSHRKDM4EALDH1A1
SCHEMBL4620115 0.72 CYP2D6 (0.62) CYP2D6HSD17B10TSHRKDM4EALDH1A1
SCHEMBL2248903 0.72 CYP2D6 (0.62) CYP2D6HSD17B10TSHRKDM4EALDH1A1
SCHEMBL14031124 0.68 CYP2D6 (0.65) CYP2D6HSD17B10TSHRKDM4EALDH1A1
SCHEMBL28859486 0.67 GPR84 (0.41) CYP2D6HSD17B10TSHRKDM4EALDH1A1
SCHEMBL27885968 0.65 CYP2D6 (0.56) CYP2D6HSD17B10TSHRKDM4EALDH1A1
SCHEMBL1759589 0.65 CYP2D6 (0.56) CYP2D6HSD17B10TSHRKDM4EALDH1A1
SCHEMBL6423324 0.65 CYP2D6 (0.60) CYP2D6HSD17B10TSHRKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108047118-B Synthetic method of 3-indolseleno alcohol organic compound 温州大学苍南研究院 2021-01-22 CN disclosed