Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14259336 | 0.86 | KMT2A (0.59) | KMT2AMAPTHTTNPC1NPSR1 | |
| SCHEMBL4285800 | 0.84 | CNR2 (0.55) | KMT2ANPC1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14259335 | 0.84 | KMT2A (0.54) | KMT2AMAPTHTTGAANPC1 | |
| SCHEMBL11138844 | 0.83 | LMNA (0.60) | KMT2AMAPTHTTNPC1NPSR1 | |
| SCHEMBL28418658 | 0.83 | TDP1 (0.60) | KMT2AMAPTHTTNPC1NPSR1 | |
| SCHEMBL14259339 | 0.83 | KMT2A (0.56) | KMT2AHTTNPC1NPSR1SMN1; SMN2 | |
| SCHEMBL27557414 | 0.83 | ALDH1A1 (0.55) | KMT2AMAPTHTTNPC1NPSR1 | |
| SCHEMBL723171 | 0.82 | AKR1C3 (0.57) | KMT2AMAPTGAAALDH1A1HPGD | |
| SCHEMBL29881091 | 0.82 | AKR1C3 (0.57) | KMT2AMAPTGAAALDH1A1HPGD | |
| SCHEMBL14259338 | 0.82 | CYP4F2 (0.55) | KMT2AMAPTGAANPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112955113-A | Antimicrobial binding compositions comprising glycerol derivatives and bicyclic compounds | 科莱恩国际有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-112351970-A | Method for forming 2-hydroxypyridine-1-oxide or derivative thereof | 科莱恩国际有限公司 | 2021-02-09 | — | — | CN | disclosed |