Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183606 | 0.89 | FFAR2 (0.51) | ABCB1RIPK1GPR119FFAR2 | |
| SCHEMBL475744 | 0.89 | FFAR2 (0.51) | ABCB1RIPK1GPR119FFAR2 | |
| SCHEMBL29040317 | 0.89 | FFAR2 (0.51) | ABCB1RIPK1GPR119FFAR2 | |
| SCHEMBL30720983 | 0.89 | FFAR2 (0.51) | ABCB1RIPK1GPR119FFAR2 | |
| SCHEMBL5156869 | 0.89 | FFAR2 (0.51) | ABCB1RIPK1GPR119FFAR2 | |
| SCHEMBL859599 | 0.89 | FFAR2 (0.51) | ABCB1RIPK1GPR119FFAR2 | |
| SCHEMBL2896922 | 0.89 | FFAR2 (0.51) | ABCB1RIPK1GPR119FFAR2 | |
| SCHEMBL475745 | 0.89 | FFAR2 (0.51) | ABCB1RIPK1GPR119FFAR2 | |
| SCHEMBL310430 | 0.88 | KCNH2 (0.39) | GPR119KCNH2 | |
| SCHEMBL22546664 | 0.88 | KCNH2 (0.39) | GPR119KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |