Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.88 |
| ▸ | NPC1 | O15118 | 12/20 | 0.88 |
| ▸ | CHKA | P35790 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944411 | 1.00 | RAB9A (0.88) | RAB9ANPC1CHKAMAPTMAOA | |
| SCHEMBL24071962 | 1.00 | RAB9A (0.88) | RAB9ANPC1CHKAMAPTMAOA | |
| SCHEMBL30944422 | 1.00 | RAB9A (0.88) | RAB9ANPC1CHKAMAPTMAOA | |
| SCHEMBL30944350 | 1.00 | RAB9A (0.88) | RAB9ANPC1CHKAMAPTMAOA | |
| SCHEMBL28529297 | 1.00 | RAB9A (0.88) | RAB9ANPC1CHKAMAPTMAOA | |
| SCHEMBL24071576 | 0.89 | RAB9A (0.85) | RAB9ANPC1CHKAMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL31419712 | 0.86 | RAB9A (0.69) | RAB9ANPC1CHKAMAPTMAOA | |
| SCHEMBL24071463 | 0.86 | NPC1 (0.73) | RAB9ANPC1CHKAMAPTALDH1A1 | |
| SCHEMBL24071516 | 0.86 | RAB9A (0.72) | RAB9ANPC1CHKAMAPTALDH1A1 | |
| SCHEMBL31419754 | 0.86 | RAB9A (0.72) | RAB9ANPC1CHKAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112423746-A | Novel anti-mycobacterial heterocyclic amides | 克莱斯通公司 | 2021-02-26 | — | — | CN | claimed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-112423746-A | Novel anti-mycobacterial heterocyclic amides | 克莱斯通公司 | 2021-02-26 | — | — | CN | disclosed |