Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 5/20 | 0.96 |
| ▸ | CES1 | P23141 | 5/20 | 0.96 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29505404 | 0.98 | TGM2 (1.00) | TGM2CES1LRRK2AGTR1MAOA | |
| SCHEMBL136581 | 0.98 | TGM2 (1.00) | TGM2CES1LRRK2AGTR1MAOA | |
| Water SCHEMBL8100148 | 0.96 | TGM2 (0.96) | TGM2CES1LRRK2AGTR1MAOA | |
| Nitrogen SCHEMBL29242330 | 0.94 | TGM2 (0.92) | TGM2CES1LRRK2AGTR1MAOA | |
| Alcohol SCHEMBL27855752 | 0.88 | TGM2 (0.80) | TGM2CES1LRRK2AGTR1MAOA | |
| SCHEMBL30972546 | 0.85 | TGM2 (0.77) | TGM2CES1LRRK2AGTR1CCNB2 | |
| Phenol SCHEMBL672900 | 0.85 | TGM2 (0.75) | TGM2CES1LRRK2AGTR1MAOA | |
| SCHEMBL28881913 | 0.82 | TGM2 (0.71) | TGM2CES1LRRK2AGTR1CA1 | |
| SCHEMBL11920848 | 0.82 | TGM2 (0.71) | TGM2CES1LRRK2AGTR1CA1 | |
| SCHEMBL8557 | 0.82 | CES1 (0.71) | TGM2CES1AGTR1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384769-B | Synthetic method of R-configuration 3-substituted-3-hydroxy oxindole compound | 陕西师范大学 | 2020-12-22 | — | — | CN | claimed |
| CN-109384769-B | Synthetic method of R-configuration 3-substituted-3-hydroxy oxindole compound | 陕西师范大学 | 2020-12-22 | — | — | CN | disclosed |