Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | BMPR1B | O00238 | 3/20 | 0.44 |
| ▸ | BMPR1A | P36894 | 3/20 | 0.44 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28522500 | 1.00 | CYP1A2 (0.53) | CYP1A2LMNAGBA1CYP2D6CNR1 | |
| SCHEMBL28001258 | 0.87 | MEN1 (0.56) | CYP1A2LMNACNR1TSHRMEN1 | |
| SCHEMBL30784206 | 0.79 | ALDH1A1 (0.48) | CYP1A2MEN1CYP2C19KMT2ASMYD3 | |
| SCHEMBL30784564 | 0.79 | SMYD3 (0.42) | CYP1A2CNR1MEN1CYP2C19KMT2A | |
| SCHEMBL30783917 | 0.79 | KMT2A (0.50) | CYP1A2MEN1CYP2C19KMT2ASMYD3 | |
| SCHEMBL20995120 | 0.78 | BMPR1B (0.62) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL20995270 | 0.78 | BMPR1B (0.62) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL20995122 | 0.78 | BMPR1B (0.62) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL30784312 | 0.74 | CYP1A2 (0.55) | CYP1A2LMNAMEN1CYP2C19KMT2A | |
| SCHEMBL26563671 | 0.74 | CYP1A2 (0.55) | CYP1A2LMNAMEN1CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341347-B | Synthetic method of ambroxol hydrochloride | 中国药科大学 | 2022-03-08 | — | — | CN | claimed |
| CN-112341347-A | Synthetic method of ambroxol hydrochloride | 中国药科大学 | 2021-02-09 | — | — | CN | claimed |
| CN-112341347-B | Synthetic method of ambroxol hydrochloride | 中国药科大学 | 2022-03-08 | — | — | CN | disclosed |
| CN-112341347-B | Synthetic method of ambroxol hydrochloride | 中国药科大学 | 2022-03-08 | — | — | CN | disclosed |
| CN-112341347-A | Synthetic method of ambroxol hydrochloride | 中国药科大学 | 2021-02-09 | — | — | CN | disclosed |
| CN-112341347-A | Synthetic method of ambroxol hydrochloride | 中国药科大学 | 2021-02-09 | — | — | CN | disclosed |