Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28522855

C1CCOC1.CCC(O)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
TSHR P16473 2/20 0.35
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dioxane SCHEMBL28118854 0.88 TTR (0.40) TSHRUSP2
Tetrahydrofuran SCHEMBL23711833 0.86 TSHR (0.56) ALDH1A1TSHRUSP2
Oxirane SCHEMBL27471704 0.84
SCHEMBL28118855 0.82 TSHR (0.35) TSHR
Tetrahydrofuran SCHEMBL10986188 0.81 ALDH1A1 (0.40) ALDH1A1TSHRUSP2
Tetrahydrofuran SCHEMBL10386650 0.80 ALDH1A1 (0.44) ALDH1A1TSHRUSP2
Tetrahydrofuran SCHEMBL28255861 0.79 ALDH1A1 (0.50) ALDH1A1TSHR
Tetrahydrofuran SCHEMBL154168 0.78
Tetrahydrofuran SCHEMBL30232 0.78
Tetrahydrofuran SCHEMBL8412489 0.78 ALDH1A1 (0.57) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115505092-A High-solid-content aqueous polyurethane resin and preparation method thereof 青海师范大学 2022-12-23 CN claimed
CN-112209842-A Polyamine synthesis method and polyamine 深圳飞扬骏研新材料股份有限公司 2021-01-12 CN claimed
CN-115505092-A High-solid-content aqueous polyurethane resin and preparation method thereof 青海师范大学 2022-12-23 CN disclosed
CN-112209842-A Polyamine synthesis method and polyamine 深圳飞扬骏研新材料股份有限公司 2021-01-12 CN disclosed