Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Tetrahydrofuran. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL8412489 | 1.00 | ALDH1A1 (0.57) | — | |
| Tetrahydrofuran SCHEMBL4858668 | 0.97 | — | — | |
| Tetrahydrofuran SCHEMBL28397015 | 0.97 | ALDH1A1 (0.53) | — | |
| Alcohol SCHEMBL4270003 | 0.97 | ALDH1A1 (0.53) | — | |
| Alcohol SCHEMBL3138912 | 0.97 | ALDH1A1 (0.53) | — | |
| Alcohol SCHEMBL15013700 | 0.97 | — | — | |
| Tetrahydrofuran SCHEMBL241626 | 0.97 | — | — | |
| Tetrahydrofuran SCHEMBL218583 | 0.97 | ALDH1A1 (0.53) | — | |
| Tetrahydrofuran SCHEMBL3893627 | 0.94 | ALDH1A1 (0.50) | — | |
| Alcohol SCHEMBL7807841 | 0.94 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1650 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515282-B | Porous silicon-carbon negative electrode and preparation method and application thereof | 原纪划(上海)新材料科技有限公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118515282-A | Porous silicon-carbon negative electrode and preparation method and application thereof | 原纪划(上海)新材料科技有限公司 | 2024-08-20 | — | — | CN | claimed |
| CN-118231773-A | High-energy-density sodium ion battery electrolyte | 江苏丰山全诺新能源科技有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-113563735-B | Dye for dye sensitized solar cell and preparation method thereof | 邯郸学院 | 2023-12-08 | — | — | CN | claimed |
| CN-117062596-A | Pharmaceutical composition | 美蒂森股份公司 | 2023-11-14 | — | — | CN | claimed |
| CN-116947927-A | Preparation method of flame retardant DOPO | 安顺学院 | 2023-10-27 | — | — | CN | claimed |
| CN-115260056-B | Cross-linking agent and preparation method thereof, polyimide 3D printing ink and preparation method of recyclable thermosetting polyimide product | 中国科学院兰州化学物理研究所 | 2023-06-30 | — | — | CN | claimed |
| CN-116162408-B | Organosilicon solvent-free waterproof anticorrosive paint and preparation method and application thereof | 山东福瑞斯新材料科技有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-116162408-A | Organosilicon solvent-free waterproof anticorrosive paint and preparation method and application thereof | 山东福瑞斯新材料科技有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-115777906-A | Sodium chloride nano-micron particle and preparation method and application thereof | 吉林大学 | 2023-03-14 | — | — | CN | claimed |
| CN-1539856-A | Loaded method of Non-metallocene catalyst loaded by composite carrier and polymerizing application | 扬子石油化工股份有限公司 | 2004-10-27 | — | — | CN | claimed |
| CN-1156496-C | Polythene catalyst loaded by double-carrier of magnesium chloride/kaolin and its preparation method | 中国石油化工股份有限公司 | 2004-07-07 | — | — | CN | claimed |
| CN-1136239-C | Magnesium halide/silicon dioxide loaded semi-metallocene catalyst and its preparation and use | 中国石油化工股份有限公司 | 2004-01-28 | — | — | CN | claimed |
| CN-1400226-A | Polythene catalyst loaded by double-carrier of magnesium chloride/kaolin and its preparation method | CHINA PETROCHEMICAL CORP (CN) | 2003-03-05 | — | — | CN | claimed |
| CN-1364817-A | Magnesium halide/silicon dioxide loaded semi-metallocene catalyst and its preparation and use | CHINA PETROCHEMICAL CORP (CN) | 2002-08-21 | — | — | CN | claimed |
| CN-1306014-A | Polynuclear pyridine biimine iron (or cobalt) catalyst for polymerization of olefine | CHANGCHUN APPLIED CHEMISTRY (CN) | 2001-08-01 | — | — | CN | claimed |
| EP-0328421-B1 | INFECTION-RESISTANT COMPOSITIONS, MEDICAL DEVICES AND SURFACES AND METHODS FOR PREPARING AND USING SAME | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1993-04-14 | — | — | EP | claimed |
| US-4950750-A | Glycolipid containing N-glycolylneuraminic acid and method of producing the same | MECT CORPORATION (JP) | 1990-08-21 | — | — | US | claimed |
| EP-0328421-A2 | Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1989-08-16 | — | — | EP | claimed |
| US-4175009-A | Separation of alcohol from tetrahydrofuran | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-11-20 | — | — | US | claimed |