SCHEMBL2852291

SCHEMBL2852291

O=C1OCC2CC=CC=C12

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA7 P36544 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9281136 0.81
SCHEMBL8608379 0.68 MAOA (0.33)
SCHEMBL1078392 0.68
SCHEMBL8857064 0.65 CYP19A1 (0.30)
SCHEMBL27526976 0.65 MAPT (0.30)
SCHEMBL527137 0.64
SCHEMBL6487916 0.64 MAOA (0.31)
SCHEMBL18551254 0.64
SCHEMBL9900722 0.64
SCHEMBL23181453 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103183654-B Separation purification preparation process for activated monomers of celery seeds UNIVTAISHAN MEDICAL 2014-11-05 CN claimed
CN-101978980-B Szechuan lovage rhizome total phthalide extract SHENZHEN TAIKANG PHARMACY CO LTD 2012-07-25 CN claimed
CN-101978980-A Szechuan lovage rhizome total phthalide extract SHENZHEN TAIKANG PHARMACY CO LTD 2011-02-23 CN claimed
CN-100506225-C Pharmaceutical use, medicine composition and preparation process of angelica oil components JIANGXI QINGFENG PHARMACEUTICA (CN) 2009-07-01 CN claimed
CN-1810241-A Pharmaceutical use, medicine composition and prepn process of angelica oil components JIANGXI QINGFENG PHARMACEUTICA (CN) 2006-08-02 CN claimed
CN-113549038-B Polysubstituted isobenzofuran compound and application thereof 常州大学 2023-05-23 CN disclosed
CN-106727601-A One kind treats pleuritic medicine 郑州欧印数字科技有限公司 2017-05-31 CN disclosed
CN-105213370-A Application of phthalide compound EVERFRONT BIOTECH INC 2016-01-06 CN disclosed
CN-104547781-A Traditional Chinese medicine agentia for treating arteriosclerosis and preparation of thereof WANG SHIGUO 2015-04-29 CN disclosed
CN-103183654-A Separation purification preparation process for activated monomers of celery seeds UNIVTAISHAN MEDICAL 2013-07-03 CN disclosed
CN-101978980-B Szechuan lovage rhizome total phthalide extract SHENZHEN TAIKANG PHARMACY CO LTD 2012-07-25 CN disclosed
CN-102283197-A Application of o-hydroxybenzoic acid lactone compounds to alleviation of poisoning of amide herbicides on paddy rice 2011-12-21 CN disclosed
EP-1973877-A2 CANNIBINOID RECEPTOR MODULATORS SCHERING CORPORATION (US) 2008-10-01 EP disclosed
CN-101071130-A Method for establishing quality standard fingerprint spectrum of Chinese material medica CHINA GUANGZHOU ANALYSIS AND T (CN) 2007-11-14 CN disclosed
WO-2007084450-A2 CANNIBINOID RECEPTOR MODULATORS SCHERING CORPORATION (US) 2007-07-26 WO disclosed
CN-1810241-A Pharmaceutical use, medicine composition and prepn process of angelica oil components JIANGXI QINGFENG PHARMACEUTICA (CN) 2006-08-02 CN disclosed
US-20060014735-A1 Use of urea variants as affinity ligands CYTIVA BIOPROCESS R&D AB (SE) 2006-01-19 US disclosed
WO-2004039843-A1 IMMUNOGLOBULIN G BINDING POCKET AMERSHAM BIOSCIENCES AB (SE) 2004-05-13 WO disclosed
WO-2004039765-A1 USE OF UREA VARIANTS AS AFFINITY LIGANDS AMERSHAM BIOSCIENCES AB (SE) 2004-05-13 WO disclosed
WO-2003082310-A1 COMPOSITION AND METHOD FOR THE TREATMENT OR PREVENTION OF IL-1 MEDIATED DISORDERS GENERAL NUTRITION INVESTMENT COMPANY (US) 2003-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060014735-A1 Use of urea variants as affinity ligands IGLV6-57, FCGR2A, FCGR3B CHRNB2 2662/4885CHRNB4 2148/4885CHRNA3 1719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.