Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | SREBF2 | Q12772 | 2/20 | 0.57 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | EIF4E | P06730 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19196715 | 0.90 | CYP19A1 (0.67) | CYP19A1KDM4EKMT2AARSREBF2 | |
| SCHEMBL26121417 | 0.88 | HSD17B1 (0.63) | CYP19A1KDM4EKMT2ASREBF2HSD17B1 | |
| SCHEMBL12171802 | 0.84 | CYP19A1 (0.67) | CYP19A1KDM4EKMT2AHSD17B1HSD17B2 | |
| SCHEMBL4281217 | 0.83 | RAB9A (0.75) | CYP19A1KDM4EKMT2AARSREBF2 | |
| SCHEMBL11455457 | 0.83 | RAB9A (0.75) | CYP19A1KDM4EKMT2AARSREBF2 | |
| SCHEMBL31678026 | 0.82 | MAPT (0.72) | CYP19A1KDM4EKMT2AHSD17B1HSD17B2 | |
| SCHEMBL26136626 | 0.82 | MAPT (0.72) | CYP19A1KDM4EKMT2AHSD17B1HSD17B2 | |
| SCHEMBL31677707 | 0.82 | MAPT (0.72) | CYP19A1KDM4EKMT2AHSD17B1HSD17B2 | |
| SCHEMBL26135516 | 0.82 | MAPT (0.72) | CYP19A1KDM4EKMT2AHSD17B1HSD17B2 | |
| SCHEMBL2781370 | 0.82 | KDM4E (0.85) | CYP19A1KDM4EKMT2AARSREBF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204507-B | Process for producing 2-aryl-4-alkylthiazole compound | 浙江大学 | 2021-03-02 | — | — | CN | disclosed |