SCHEMBL28523218

SCHEMBL28523218

CC(C)(C)OC(=O)NC(Cc1c(Br)cccc1[N+](=O)[O-])C(=O)OC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSS P25774 6/20 0.44
CTSK P43235 5/20 0.44
GSTP1 P09211 1/20 0.43
GSTM2 P28161 1/20 0.43
CTSB P07858 3/20 0.41
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
ITGA4 P13612 1/20 0.40
ITGB7 P26010 1/20 0.40
CTSL P07711 1/20 0.39
ALDH1A1 P00352 3/20 0.39
POLB P06746 1/20 0.39
BCL2 P10415 2/20 0.38
MCL1 Q07820 1/20 0.38
MAPT P10636 2/20 0.38
EPHX2 P34913 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28523141 0.82 CTSS (0.47) CTSSCTSKCTSBCTSLALDH1A1
SCHEMBL28524201 0.82 CTSS (0.47) CTSSCTSKCTSBCTSLALDH1A1
SCHEMBL28532406 0.82 CTSS (0.47) CTSSCTSKCTSBCTSLALDH1A1
SCHEMBL8396469 0.79 TACR1 (0.46) CTSSCTSKGSTP1GSTM2ALDH1A1
SCHEMBL3775078 0.78 GSTP1 (0.46) CTSSCTSKGSTP1GSTM2CTSB
SCHEMBL17258263 0.78 AAK1 (0.44) CTSSCTSKGSTP1GSTM2CTSB
SCHEMBL17258264 0.78 AAK1 (0.44) CTSSCTSKGSTP1GSTM2CTSB
SCHEMBL2234976 0.77 PPARA (0.46) CTSSCTSKGSTP1GSTM2CTSB
SCHEMBL15565704 0.77 PPARA (0.46) CTSSCTSKGSTP1GSTM2CTSB
SCHEMBL15947606 0.76 GSTP1 (0.52) CTSSCTSKGSTP1GSTM2CTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105916836-B Method for producing 2-fluoro-4-borono-L-phenylalanine and precursor thereof 斯特拉制药公司 2021-02-09 CN disclosed