Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.47 |
| ▸ | CTSK | P43235 | 7/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28523141 | 0.86 | CTSS (0.47) | CTSSCTSKCTSBALDH1A1MAPT | |
| SCHEMBL28532406 | 0.86 | CTSS (0.47) | CTSSCTSKCTSBALDH1A1MAPT | |
| SCHEMBL28523218 | 0.82 | CTSS (0.44) | CTSSCTSKCTSBALDH1A1MAPT | |
| SCHEMBL4584520 | 0.81 | PTPN1 (0.55) | CTSSCTSKSCN9ACTSBPTPN1 | |
| SCHEMBL1529787 | 0.81 | PTPN1 (0.55) | CTSSCTSKSCN9ACTSBPTPN1 | |
| SCHEMBL30825600 | 0.81 | CTSS (0.47) | CTSSCTSKSCN9ACTSBPTPN1 | |
| SCHEMBL28989417 | 0.80 | TACR1 (0.48) | CTSSCTSKCTSBCTSLAAK1 | |
| SCHEMBL30681226 | 0.79 | AAK1 (0.42) | CTSSCTSKSCN9ACTSBALDH1A1 | |
| SCHEMBL30681530 | 0.79 | AAK1 (0.42) | CTSSCTSKSCN9ACTSBALDH1A1 | |
| SCHEMBL30825613 | 0.79 | KLK5 (0.43) | CTSSCTSKSCN9ACTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916836-B | Method for producing 2-fluoro-4-borono-L-phenylalanine and precursor thereof | 斯特拉制药公司 | 2021-02-09 | — | — | CN | disclosed |