Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30316975 | 0.90 | LMNA (0.49) | LMNAHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7229502 | 0.85 | KDM4E (0.45) | HDAC3HDAC1HDAC2NCOR2HDAC10 | |
| SCHEMBL28678637 | 0.78 | LMNA (0.36) | LMNAHDAC3HDAC1PTGER4SMN1; SMN2 | |
| SCHEMBL28505377 | 0.78 | PTGER4 (0.39) | HDAC3HDAC1HDAC2NCOR2HDAC10 | |
| SCHEMBL15577833 | 0.77 | LMNA (0.51) | LMNAHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL28538491 | 0.77 | NPC1 (0.62) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL8720377 | 0.77 | HDAC3 (0.41) | LMNAHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL28505378 | 0.76 | HDAC3 (0.51) | LMNAHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL27972316 | 0.76 | NCEH1 (0.43) | LMNAPTGER4NPC1RAB9AALDH1A1 | |
| SCHEMBL6201094 | 0.75 | MAPT (0.52) | LMNAHDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230099441-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | GENEROS BIOPHARMA LTD. (CN) | 2023-03-30 | — | — | US | disclosed |
| CN-111848598-A | Heterocyclic ring-containing compound, application thereof and composition containing heterocyclic ring-containing compound | 健艾仕生物医药有限公司 | 2020-10-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230099441-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | STAT5A, STAT5B, JAK2 | LMNA 4482/4885HDAC3 43/4885HDAC1 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.