Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28523832 | 0.85 | LMNA (0.44) | KDM4EPTGER4TDP1SMN1; SMN2HDAC3 | |
| SCHEMBL28772834 | 0.82 | MAPT (0.58) | KDM4ERECQLTDP1THRBSMN1; SMN2 | |
| SCHEMBL5954193 | 0.81 | POLB (0.48) | KDM4ERECQLTDP1THRBSMN1; SMN2 | |
| SCHEMBL10993444 | 0.81 | KDM4E (0.45) | KDM4ERECQLTDP1THRBSMN1; SMN2 | |
| SCHEMBL27776939 | 0.79 | KDM4E (0.39) | KDM4ERECQLPTGER4TDP1THRB | |
| SCHEMBL6513522 | 0.78 | KDM4E (0.68) | KDM4ESMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL6382404 | 0.78 | KDM4E (0.48) | KDM4ERECQLTDP1THRBSMN1; SMN2 | |
| SCHEMBL6565047 | 0.78 | KDM4E (0.43) | KDM4ERECQLTDP1THRBSMN1; SMN2 | |
| SCHEMBL742957 | 0.78 | PTGER4 (0.54) | KDM4ERECQLPTGER4TDP1THRB | |
| SCHEMBL7366151 | 0.77 | CA12 (0.62) | RECQLHDAC3HDAC1HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506738-B1 | Treatment of viral infections. More particularly, the invention provides benzimidazolone derivatives for the treatment of respiratory syncytial virus infection. | BRISTOL-MYERS SQUIBB COMPANY | 2003-01-14 | — | — | US | disclosed |
| WO-2002026228-A1 | BENZIMIDAZOLONE ANTIVIRAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-04-04 | — | — | WO | disclosed |