Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20411416 | 1.00 | FPR2 (0.51) | FPR2SLC6A2SLC6A4SLC6A3BACE1 | |
| SCHEMBL18264209 | 0.86 | FPR2 (0.49) | FPR2KDM1AMAOAMAOBNPC1 | |
| SCHEMBL22097655 | 0.86 | FPR2 (0.49) | FPR2KDM1AMAOAMAOBNPC1 | |
| SCHEMBL18264211 | 0.86 | FPR2 (0.49) | FPR2KDM1AMAOAMAOBNPC1 | |
| SCHEMBL20411436 | 0.86 | FPR2 (0.49) | FPR2KDM1AMAOAMAOBNPC1 | |
| SCHEMBL18264207 | 0.86 | FPR2 (0.49) | FPR2KDM1AMAOAMAOBNPC1 | |
| SCHEMBL18264263 | 0.86 | FPR2 (0.49) | FPR2KDM1AMAOAMAOBNPC1 | |
| SCHEMBL2359242 | 0.81 | MAPT (0.56) | SLC6A2SLC6A4SLC6A3KDM1AMAOA | |
| SCHEMBL2359239 | 0.81 | MAPT (0.56) | SLC6A2SLC6A4SLC6A3KDM1AMAOA | |
| SCHEMBL18700413 | 0.76 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3BACE1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185452-A | Urea derivatives or pharmaceutically acceptable salts thereof | 杏林制药株式会社 | 2021-07-30 | — | — | CN | disclosed |
| CN-107849049-B | Urea derivatives or pharmaceutically acceptable salts thereof | 杏林制药株式会社 | 2021-03-16 | — | — | CN | disclosed |