Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 2/20 | 0.44 |
| ▸ | EDNRB | P24530 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18264207 | 1.00 | FPR2 (0.49) | FPR2L3MBTL1KDM1AMAOAMAOB | |
| SCHEMBL20411436 | 1.00 | FPR2 (0.49) | FPR2L3MBTL1KDM1AMAOAMAOB | |
| SCHEMBL18264263 | 1.00 | FPR2 (0.49) | FPR2L3MBTL1KDM1AMAOAMAOB | |
| SCHEMBL18264209 | 1.00 | FPR2 (0.49) | FPR2L3MBTL1KDM1AMAOAMAOB | |
| SCHEMBL18264211 | 1.00 | FPR2 (0.49) | FPR2L3MBTL1KDM1AMAOAMAOB | |
| SCHEMBL20411416 | 0.86 | FPR2 (0.51) | FPR2KDM1AMAOAMAOBRAB9A | |
| SCHEMBL28523929 | 0.86 | FPR2 (0.51) | FPR2KDM1AMAOAMAOBRAB9A | |
| SCHEMBL10289077 | 0.80 | RAB9A (0.57) | L3MBTL1KDM1AMAOAMAOBEDNRA | |
| SCHEMBL432751 | 0.80 | RAB9A (0.57) | L3MBTL1KDM1AMAOAMAOBEDNRA | |
| SCHEMBL18596476 | 0.80 | RAB9A (0.57) | L3MBTL1KDM1AMAOAMAOBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331884-B1 | UREA DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF | KYORIN SEIYAKU KK (JP) | 2020-06-17 | — | — | EP | disclosed |