Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | CHAT | P28329 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27659522 | 0.91 | KDM4E (0.48) | TTRALOX5PTGS1PTGS2KDM4E | |
| SCHEMBL698718 | 0.87 | TTR (0.53) | TTRALOX5PTGS1PTGS2KDM4E | |
| SCHEMBL698717 | 0.87 | TTR (0.53) | TTRALOX5PTGS1PTGS2KDM4E | |
| SCHEMBL27322505 | 0.86 | CYP19A1 (0.48) | TTRALOX5PTGS1PTGS2KDM4E | |
| SCHEMBL28128701 | 0.75 | CYP19A1 (0.58) | KDM4EALDH1A1HPGDCYP19A1MAOA | |
| Benzoic Acid SCHEMBL20968915 | 0.75 | TTR (0.51) | TTRALOX5PTGS1PTGS2ALDH1A1 | |
| Toluene SCHEMBL27930865 | 0.74 | CYP19A1 (0.47) | TTRALOX5PTGS1PTGS2KDM4E | |
| SCHEMBL27498123 | 0.74 | TTR (0.44) | TTRALOX5PTGS1PTGS2KDM4E | |
| SCHEMBL28413170 | 0.73 | CYP2D6 (0.46) | TTRALOX5PTGS1PTGS2KDM4E | |
| SCHEMBL28503270 | 0.73 | ALDH1A1 (0.48) | TTRALOX5PTGS1PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608455-B | Synthesis method of indazolo [2,3-a ] quinoline and derivatives thereof | 常州大学 | 2021-03-02 | — | — | CN | disclosed |