SCHEMBL698717

SCHEMBL698717

Cc1cc(C)c(/C=C/c2ccccc2)c(C)c1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.53
ALOX5 P09917 1/20 0.53
PTGS1 P23219 1/20 0.53
PTGS2 P35354 1/20 0.53
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
NFE2L2 Q16236 3/20 0.47
CHAT P28329 3/20 0.46
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MAOB P27338 2/20 0.42
RELA Q04206 2/20 0.42
CYP19A1 P11511 1/20 0.42
MAOA P21397 1/20 0.42
TRPA1 O75762 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL698718 1.00 TTR (0.53) TTRALOX5PTGS1PTGS2KDM4E
SCHEMBL28524007 0.87 TTR (0.46) TTRALOX5PTGS1PTGS2KDM4E
Benzoic Acid SCHEMBL20968915 0.86 TTR (0.51) TTRALOX5PTGS1PTGS2ALDH1A1
SCHEMBL12500811 0.82 NFE2L2 (0.56) TTRALOX5PTGS1PTGS2KDM4E
SCHEMBL12500812 0.82 NFE2L2 (0.56) TTRALOX5PTGS1PTGS2KDM4E
SCHEMBL699401 0.81 RAPGEF4 (0.43) KDM4EALDH1A1HPGDMAPT
SCHEMBL699400 0.81 RAPGEF4 (0.43) KDM4EALDH1A1HPGDMAPT
SCHEMBL12500726 0.79 ALOX5 (0.59) TTRALOX5PTGS1PTGS2KDM4E
SCHEMBL12500728 0.79 ALOX5 (0.59) TTRALOX5PTGS1PTGS2KDM4E
SCHEMBL27969136 0.79 ALOX5 (0.59) TTRALOX5PTGS1PTGS2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460994-B1 Method and apparatus to make evident one or more shocks received by a substrate HUTCHINSON SA (FR) 1995-03-15 EP claimed
US-5242830-A Detection of impact with fluorescent indicators by embedding microcapsules and releasing HUTCHINSON (FR) 1993-09-07 US claimed
EP-0460994-A1 Method and apparatus to make evident one or more shocks received by a substrate HUTCHINSON S.A. une SociÀ©té Anonyme dotée d'un Conseil de Surveillance et d'un Directoire (FR) 1991-12-11 EP claimed
US-12404221-B2 Methods of arene alkenylation UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-09-02 US disclosed
US-20230234900-A1 METHODS OF ARENE ALKENYLATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2023-07-27 US disclosed
WO-2021074275-A1 EFFECTIVE PHOTOMODULATION OF LANTHANIDE (III) ION LUMINESCENCE IN THE VISIBLE OR NEAR-INFRARED RANGE UNIVERSITE DE RENNES 1 (FR) 2021-04-22 WO disclosed
US-9925153-B2 Therapeutic agents for skin diseases and conditions STC.UNM (US) 2018-03-27 US disclosed
US-9868873-B2 Photochromic security enabled ink for digital offset printing applications XEROX CORPORATION (US) 2018-01-16 US disclosed
US-20160287531-A1 THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS STC.UNM 2016-10-06 US disclosed
US-8980954-B2 Substituted cis- and trans-stilbenes as therapeutic agents STC.UNM (US) 2015-03-17 US disclosed
US-8703388-B2 Optical data storage media GENERAL ELECTRIC COMPANY (US) 2014-04-22 US disclosed
EP-1591830-A2 Reimageable medium Xerox Corporation (US) 2005-11-02 EP disclosed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed
EP-0460994-B1 Method and apparatus to make evident one or more shocks received by a substrate HUTCHINSON SA (FR) 1995-03-15 EP disclosed
US-5242830-A Detection of impact with fluorescent indicators by embedding microcapsules and releasing HUTCHINSON (FR) 1993-09-07 US disclosed
EP-0460994-A1 Method and apparatus to make evident one or more shocks received by a substrate HUTCHINSON S.A. une SociÀ©té Anonyme dotée d'un Conseil de Surveillance et d'un Directoire (FR) 1991-12-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160287531-A1 THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS CUTA, TSLP, ELANE TTR 76/4885ALOX5 977/4885PTGS1 1081/4885
US-20230234900-A1 METHODS OF ARENE ALKENYLATION CYBB, CBR3, AHR TTR 2602/4885ALOX5 117/4885PTGS1 2007/4885
US-12404221-B2 Methods of arene alkenylation CYBB, CBR3, AHR TTR 2602/4885ALOX5 117/4885PTGS1 2007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.