Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 13/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14254170 | 0.85 | NFE2L2 (0.55) | NFE2L2MAOBCYP19A1MAOAHTR2A | |
| SCHEMBL6303896 | 0.81 | CYP19A1 (0.59) | NFE2L2MAOBCYP19A1MAOA | |
| SCHEMBL6303895 | 0.81 | CYP19A1 (0.59) | NFE2L2MAOBCYP19A1MAOA | |
| SCHEMBL7005405 | 0.80 | NFE2L2 (0.53) | NFE2L2MAOBHTR2AHTR2CKCNH2 | |
| Hydrochloric Acid SCHEMBL6388867 | 0.79 | CYP19A1 (0.57) | NFE2L2MAOBCYP19A1MAOA | |
| Hydrochloric Acid SCHEMBL6388866 | 0.79 | CYP19A1 (0.57) | NFE2L2MAOBCYP19A1MAOA | |
| SCHEMBL27900227 | 0.78 | CYP1B1 (0.44) | NFE2L2MAOBCYP19A1MAOA | |
| SCHEMBL15566094 | 0.78 | MAOB (0.54) | NFE2L2MAOBCYP19A1MAOA | |
| SCHEMBL15566097 | 0.78 | MAOB (0.54) | NFE2L2MAOBCYP19A1MAOA | |
| SCHEMBL28531057 | 0.78 | MAOA (0.46) | NFE2L2MAOBCYP19A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608455-B | Synthesis method of indazolo [2,3-a ] quinoline and derivatives thereof | 常州大学 | 2021-03-02 | — | — | CN | disclosed |