SCHEMBL28524017

SCHEMBL28524017

NC(=O)c1cc(C2CC2)cc(C(F)(F)F)c1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPN5 P54829 1/20 0.47
CNR1 P21554 3/20 0.46
CYP2C9 P11712 1/20 0.44
CES2 O00748 2/20 0.44
NOTUM Q6P988 1/20 0.41
GAA P10253 2/20 0.41
HTR2C P28335 4/20 0.38
DHODH Q02127 1/20 0.38
ACLY P53396 1/20 0.37
ATF1 P18846 1/20 0.36
NFKB1 P19838 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
EPHX1 P07099 1/20 0.36
DGAT1 O75907 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21609790 0.85 CNR1 (0.47) PTPN5CNR1CES2NOTUMACLY
SCHEMBL29565302 0.85 CNR1 (0.47) PTPN5CNR1CES2NOTUMACLY
SCHEMBL21792129 0.83 ALDH1A1 (0.49) PTPN5CNR1CES2NOTUMGAA
SCHEMBL627995 0.80 CES2 (0.67) CES2NOTUMGAADHODHATF1
SCHEMBL29700845 0.80 CES2 (0.41) PTPN5CNR1CES2NOTUMGAA
SCHEMBL29565141 0.80 NOTUM (0.59) CNR1CES2NOTUMGAANFKB1
SCHEMBL16729325 0.80 NOTUM (0.59) CNR1CES2NOTUMGAANFKB1
SCHEMBL21609867 0.78 NPSR1 (0.42) PTPN5CNR1CYP2C9GAA
Hydrochloric Acid SCHEMBL4372326 0.78 CES2 (0.64) CES2NOTUMGAADHODHATF1
Hydrochloric Acid SCHEMBL4027010 0.78 CES2 (0.64) CES2NOTUMGAADHODHATF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112351978-A Pesticidally active azole-amide compounds 先正达参股股份有限公司 2021-02-09 CN disclosed