Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005151 | 0.90 | TYR (0.53) | TYRHPGDHTTNPC1MAPK1 | |
| SCHEMBL13057531 | 0.84 | GABRA1 (0.50) | GABRA1GABRB2TYRKDM4EALDH1A1 | |
| SCHEMBL5313081 | 0.83 | TYR (0.64) | TYRHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28956820 | 0.83 | TYR (0.64) | TYRHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1424910 | 0.83 | TYR (0.64) | TYRHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28354725 | 0.80 | CTRC (0.38) | TYRHPGDHTTNPC1MAPK1 | |
| SCHEMBL4955648 | 0.80 | HPGD (0.48) | TYRHPGDHTTNPC1MAPK1 | |
| SCHEMBL23387415 | 0.80 | PRKCI (0.46) | TYRHPGDKDM4EALDH1A1ELANE | |
| SCHEMBL5676906 | 0.79 | TYR (0.53) | GABRA1GABRB2TYRHTTESR1 | |
| SCHEMBL62288 | 0.78 | TYR (0.49) | TYRHPGDHTTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105837839-B | Polytetrafluoroethylene oil-based solvent dispersion, polytetrafluoroethylene-containing epoxy resin composition, and cured product thereof | 三菱铅笔株式会社 | 2021-02-02 | — | — | CN | disclosed |