Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG4B | Q9Y4P1 | 12/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28529715 | 0.80 | ATG4B (0.64) | ATG4BLMNAMEN1KMT2ARAB9A | |
| SCHEMBL28524547 | 0.79 | ATG4B (0.62) | ATG4BLMNAMEN1KMT2ARAB9A | |
| SCHEMBL28524561 | 0.78 | LMNA (0.62) | ATG4BLMNAMEN1KMT2ARAB9A | |
| SCHEMBL881339 | 0.78 | LMNA (0.84) | ATG4BLMNAMEN1KMT2ARAB9A | |
| SCHEMBL18529282 | 0.76 | ATG4B (1.00) | ATG4BLMNAMEN1KMT2ARAB9A | |
| SCHEMBL18529273 | 0.76 | ATG4B (1.00) | ATG4BLMNAMEN1KMT2ARAB9A | |
| SCHEMBL28531345 | 0.76 | ATG4B (0.58) | ATG4BLMNAMEN1KMT2ARAB9A | |
| SCHEMBL18529262 | 0.75 | ATG4B (1.00) | ATG4BLMNAMEN1KMT2ARAB9A | |
| SCHEMBL8236728 | 0.75 | LMNA (0.74) | ATG4BLMNAMEN1KMT2ARAB9A | |
| SCHEMBL28523220 | 0.75 | MEN1 (0.70) | ATG4BLMNAMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503569-B | Thiazole derivative and preparation method and application thereof | 山东大学 | 2021-01-15 | — | — | CN | claimed |
| CN-109503569-B | Thiazole derivative and preparation method and application thereof | 山东大学 | 2021-01-15 | — | — | CN | disclosed |